SCHEMBL29508145

SCHEMBL29508145

CCCOc1ccc(OCCCCN2CCOCC2)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.82
MAPK1 P28482 2/20 0.82
CYP1A2 P05177 1/20 0.82
CHRM2 P08172 1/20 0.82
CHRM1 P11229 1/20 0.82
HTR2A P28223 1/20 0.82
SCN1A P35498 1/20 0.82
HTR2B P41595 1/20 0.82
KCNH2 Q12809 1/20 0.82
SCN2A Q99250 1/20 0.82
SIGMAR1 Q99720 1/20 0.82
SCN3A Q9NY46 1/20 0.82
HRH3 Q9Y5N1 1/20 0.82
LMNA P02545 2/20 0.80
USP2 O75604 1/20 0.80
KDM4E B2RXH2 2/20 0.66
HTT P42858 1/20 0.66
SMN1; SMN2 Q16637 2/20 0.61
THRB P10828 2/20 0.61
KMT2A Q03164 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23804878 0.95 HRH3 (0.91) ALDH1A1MAPK1CYP1A2CHRM2CHRM1
Pramoxine SCHEMBL26020 0.90 ALDH1A1 (1.00) ALDH1A1MAPK1CYP1A2CHRM2CHRM1
Pramoxine SCHEMBL180542 0.89 LMNA (1.00) ALDH1A1MAPK1CYP1A2CHRM2CHRM1
Pramoxine SCHEMBL4435138 0.88 ALDH1A1 (0.94) ALDH1A1MAPK1CYP1A2CHRM2CHRM1
SCHEMBL12835047 0.88 ALDH1A1 (0.72) ALDH1A1MAPK1CYP1A2CHRM2CHRM1
SCHEMBL29508030 0.88 ALDH1A1 (0.72) ALDH1A1MAPK1CYP1A2CHRM2CHRM1
SCHEMBL29508217 0.87 ALDH1A1 (0.88) ALDH1A1MAPK1CYP1A2CHRM2CHRM1
SCHEMBL10200149 0.86 ALDH1A1 (0.70) ALDH1A1MAPK1CYP1A2CHRM2CHRM1
SCHEMBL29508133 0.86 ALDH1A1 (0.75) ALDH1A1MAPK1CYP1A2CHRM2CHRM1
SCHEMBL16314629 0.84 HRH3 (0.68) ALDH1A1MAPK1CYP1A2CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022054926-A1 AUTOPHAGY ACTIVATING COMPOSITION CONTAINING MORPHOLINE DERIVATIVE AS ACTIVE INGREDIENT 国立大学法人大阪大学 2022-03-17 WO disclosed