Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3122343 | 1.00 | SLC6A5 (0.55) | SLC6A5HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2795825 | 0.86 | CCR5 (0.52) | SLC6A5HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL25715170 | 0.83 | ALDH1A1 (0.56) | SLC6A5HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL17531636 | 0.81 | ALDH1A1 (0.54) | HPGDSMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL28218777 | 0.81 | SMN1; SMN2 (0.55) | HPGDSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL13718469 | 0.80 | MAPT (0.64) | HPGDSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL27678160 | 0.80 | SLC6A5 (0.43) | SLC6A5HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL29173362 | 0.79 | CCR5 (0.47) | SLC6A5HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27452092 | 0.79 | SMN1; SMN2 (0.45) | SLC6A5HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7057959 | 0.79 | NCF1 (0.51) | HPGDSMN1; SMN2ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237088-A1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS, AND MEDICINAL APPLICATIONS THEREOF | Blueprint Medicines Corporation (US) | 2023-09-06 | — | — | EP | disclosed |
| CN-114891070-A | Anthelmintic depsipeptide compounds | 勃林格殷格翰动物保健美国公司 | 2022-08-12 | — | — | CN | disclosed |
| WO-2022094355-A1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS, AND MEDICINAL APPLICATIONS THEREOF | LENGO THERAPEUTICS, INC. (US) | 2022-05-05 | — | — | WO | disclosed |
| CN-107835818-B | Anthelmintic depsipeptide compounds | 勃林格殷格翰动物保健美国公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-106928162-B | Synthesis method of substituted N-phenyl morpholine compound | 韶远科技（上海)有限公司 | 2022-04-08 | — | — | CN | disclosed |