Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.81 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.81 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.81 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.81 |
| ▸ | HTR2A | P28223 | 1/20 | 0.81 |
| ▸ | SCN1A | P35498 | 1/20 | 0.81 |
| ▸ | HTR2B | P41595 | 1/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.81 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.81 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.81 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | USP2 | O75604 | 1/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13107094 | 0.94 | ALDH1A1 (0.73) | ALDH1A1MAPK1HRH3CYP1A2CHRM2 | |
| SCHEMBL29508224 | 0.94 | ALDH1A1 (0.78) | ALDH1A1MAPK1HRH3CYP1A2CHRM2 | |
| Pramoxine SCHEMBL26020 | 0.90 | ALDH1A1 (1.00) | ALDH1A1MAPK1HRH3CYP1A2CHRM2 | |
| Pramoxine SCHEMBL180542 | 0.88 | LMNA (1.00) | ALDH1A1MAPK1HRH3CYP1A2CHRM2 | |
| Pramoxine SCHEMBL4435138 | 0.87 | ALDH1A1 (0.94) | ALDH1A1MAPK1HRH3CYP1A2CHRM2 | |
| SCHEMBL13185215 | 0.86 | ALDH1A1 (0.70) | ALDH1A1MAPK1HRH3CYP1A2CHRM2 | |
| SCHEMBL4124442 | 0.86 | KDM4E (0.74) | ALDH1A1MAPK1HRH3CYP1A2CHRM2 | |
| SCHEMBL23804878 | 0.85 | HRH3 (0.91) | ALDH1A1MAPK1HRH3CYP1A2CHRM2 | |
| SCHEMBL29508183 | 0.84 | ALDH1A1 (0.67) | ALDH1A1MAPK1HRH3CYP1A2CHRM2 | |
| SCHEMBL14578276 | 0.83 | ALDH1A1 (0.69) | ALDH1A1MAPK1LMNAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022054926-A1 | AUTOPHAGY ACTIVATING COMPOSITION CONTAINING MORPHOLINE DERIVATIVE AS ACTIVE INGREDIENT | 国立大学法人大阪大学 | 2022-03-17 | — | — | WO | disclosed |