SCHEMBL2950995

SCHEMBL2950995

CO[Si](CCCCc1ccc(CCl)cc1)(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.38
IGF1R P08069 1/20 0.38
ALOX15 P16050 1/20 0.38
POLB P06746 1/20 0.35
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2950991 0.94 CALM1 (0.39) CALM1IGF1RALOX15POLBTAAR1
SCHEMBL25242964 0.90 CALM1 (0.44) CALM1IGF1RALOX15CYP4F2CYP4A11
SCHEMBL680307 0.86 TAAR1 (0.36) CALM1POLBCYP4F2CYP4A11TAAR1
SCHEMBL1639310 0.84 CALM1 (0.45) CALM1IGF1RALOX15POLBCYP4F2
SCHEMBL2951354 0.82 THRA (0.35) L3MBTL1THRATHRB
SCHEMBL2944386 0.81 CALM1 (0.38) CALM1IGF1RALOX15CYP4F2CYP4A11
SCHEMBL15735870 0.81 TAAR1 (0.41) CALM1POLBL3MBTL1TAAR1
SCHEMBL2748794 0.81 L3MBTL1 (0.47) TDP1L3MBTL1
SCHEMBL17077608 0.80 CALM1 (0.42) CALM1IGF1RALOX15POLBCYP4F2
SCHEMBL15735652 0.80 TAAR1 (0.40) POLBL3MBTL1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7759406-B2 Process for producing polysilsesquioxane graft polymer, pressure-sensitive adhesive, and pressure-sensitive adhesive sheet LINTEC CORPORATION (JP) 2010-07-20 US disclosed
US-20080051487-A1 Process for Producing Polysilsesquioxane Graft Polymer, Pressure-Sensitive Adhesive, and Pressure-Sensitive Adhesive Sheet LINTEC CORPORATION (JP) 2008-02-28 US disclosed