SCHEMBL295117

SCHEMBL295117

C=COC(=O)C1CCCC(C(=O)OC=C)C1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
CHRM2 P08172 2/20 0.32
CHRM4 P08173 2/20 0.32
CHRM1 P11229 2/20 0.32
CHRM3 P20309 2/20 0.32
MIF P14174 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA4 P43681 1/20 0.31
CHRNB3 Q05901 1/20 0.31
CHRNA6 Q15825 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16176171 0.92 BTK (0.38) KMT2AHTTSMN1; SMN2TDP1
SCHEMBL624466 0.91
SCHEMBL10645897 0.91 KMT2A (0.39) KMT2A
SCHEMBL476212 0.86 CES2 (0.40) KMT2AHTTSMN1; SMN2TDP1CES2
SCHEMBL19506913 0.86 KMT2A (0.32) KMT2ACHRNB2CHRNA3CHRNA4
SCHEMBL106920 0.84 CES2 (0.44) KMT2AHTTSMN1; SMN2TDP1CES2
SCHEMBL15442771 0.84 CES2 (0.44) KMT2AHTTSMN1; SMN2TDP1CES2
SCHEMBL15442922 0.84 CES2 (0.44) KMT2AHTTSMN1; SMN2TDP1CES2
SCHEMBL15443495 0.84 CES2 (0.44) KMT2AHTTSMN1; SMN2TDP1CES2
SCHEMBL15443071 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080308765-A1 Process for Preparing Vinyl Carboxylates BASF SE (DE) 2008-12-18 US claimed
US-9624317-B2 Amphiphilic macromolecular emulsifier with switchable surface activity and use thereof in preparation of polymer latex ZHEJIANG UNIVERSITY (CN) 2017-04-18 US disclosed
US-20140316049-A1 AMPHIPHILIC MACROMOLECULAR EMULSIFIER WITH SWITCHABLE SURFACE ACTIVITY AND USE THEREOF IN PREPARATION OF POLYMER LATEX ZHEJIANG UNIVERSITY (CN) 2014-10-23 US disclosed
US-8785627-B2 Copolymerizable methine and anthraquinone compounds and articles containing them Abbott Medical Optics Inc. (US) 2014-07-22 US disclosed
US-20130324717-A1 COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM Johnson & Johnson Surgical Vision, Inc. 2013-12-05 US disclosed
US-8501890-B2 Copolymerizable methine and anthraquinone compounds and articles containing them Abbott Medical Optics Inc. (US) 2013-08-06 US disclosed
US-8360576-B2 Copolymerizable methine and anthraquinone compounds and articles containing them Abbott Medical Optics Inc. (US) 2013-01-29 US disclosed
US-20130018159-A1 COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM Abbott Medical Optics Inc. (US) 2013-01-17 US disclosed
US-8188203-B2 Intraocular lens formed from a polymer of an unsaturated aryl monoazo dye containing a 2-pyrazolin-5-one, dimedone (5,5-dimethyl-1,3-cyclohexanedione), acetoacetamide, malonamide, barbituric acid or 1,3-propanedione residue; yellow light absorbers; block ultraviolet and/or violet-blue light transmission Abbott Medical Optics Inc. (US) 2012-05-29 US disclosed
EP-2261696-B1 Copolymerizable azo compounds and articles containing them ABBOTT MEDICAL OPTICS INC (US) 2012-03-14 EP disclosed
US-6689828-B2 GOOD FASTNESS TO ULTRAVIOLET LIGHT, GOOD SOLUBILITY IN VINYL MONOMERS, GOOD COLOR STRENGTH AND EXCELLENT THERMAL STABILITY. EASTMAN CHEMICAL COMPANY 2004-02-10 US disclosed
US-6630521-B2 Thermally-stable, red, colorants photopolymerizable radicals which may be copolymerized (or cured) with ethylenically-unsaturated monomers to produce colored compositions such as colored acrylic polymer coatings EASTMAN CHEMICAL COMPANY 2003-10-07 US disclosed
US-6620858-B2 Photopolymerizable compounds containing photopolymerizable unsaturated groups which can be copolymerized to form polymeric dyes that have good thermal stability and solubility EASTMAN CHEMICAL COMPANY 2003-09-16 US disclosed
US-20030134924-A1 Anthraquinone colorants containing copolymerizable vinyl groups EASTMAN CHEMICAL COMPANY 2003-07-17 US disclosed
US-20030125505-A1 Reactive anthraquinone colorant compounds and polymeric materials reacted therewith EASTMAN CHEMICAL COMPANY 2003-07-03 US disclosed
EP-1310527-A2 Anthraquinone colorants containing copolymerizable vinyl groups EASTMAN CHEMICAL COMPANY (US) 2003-05-14 EP disclosed
EP-1304360-A1 Reactive anthraquinone colorant compounds and polymeric materials reacted therewith EASTMAN CHEMICAL COMPANY (US) 2003-04-23 EP disclosed
US-20020132874-A1 Colorant compounds containing copolymerizable vinyl groups EASTMAN CHEMICAL COMPANY 2002-09-19 US disclosed
US-20020128343-A1 Colorants containing copolymerizable vinyl groups and sulfonamide linkages EASTMAN CHEMICAL COMPANY 2002-09-12 US disclosed
US-20020068725-A1 Thermally stable, anthraquinone colorants containing copolymerizable vinyl groups EASTMAN CHEMICAL COMPANY 2002-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128343-A1 Colorants containing copolymerizable vinyl groups and sulfonamide linkages SMARCD1, SMARCA2, SMARCA4 KMT2A 706/4885HTT 1636/4885SMN1; SMN2 1159/4885
US-20030134924-A1 Anthraquinone colorants containing copolymerizable vinyl groups ALAD, AAAS, ACMSD KMT2A 2162/4885HTT 1406/4885SMN1; SMN2 3412/4885
US-20130018159-A1 COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM CRY1, AAAS, CYBA KMT2A 736/4885HTT 1017/4885SMN1; SMN2 4623/4885
US-20020068725-A1 Thermally stable, anthraquinone colorants containing copolymerizable vinyl groups ALAD, AAAS, ACMSD KMT2A 1085/4885HTT 2060/4885SMN1; SMN2 3152/4885
US-20130324717-A1 COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM CRY1, AAAS, CYBA KMT2A 736/4885HTT 1017/4885SMN1; SMN2 4623/4885
US-20080308765-A1 Process for Preparing Vinyl Carboxylates MVD, MMAB, CRBN KMT2A 558/4885HTT 3842/4885SMN1; SMN2 1692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.