SCHEMBL690073

SCHEMBL690073

Fc1ccc(Br)cc1C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 1/20 0.47
DUSP3 P51452 1/20 0.47
KDM1A O60341 2/20 0.47
USP28 Q96RU2 1/20 0.42
USP25 Q9UHP3 1/20 0.42
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
MPL P40238 3/20 0.40
AR P10275 6/20 0.39
SLC22A12 Q96S37 1/20 0.38
RXRA P19793 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2B Q13224 1/20 0.37
HCAR1 Q9BXC0 1/20 0.36
DGAT1 O75907 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29890371 1.00 PTPN7 (0.47) PTPN7DUSP3KDM1AUSP28USP25
SCHEMBL28558021 0.82 KDM1A (0.37) PTPN7DUSP3KDM1AUSP28USP25
SCHEMBL4435565 0.82 GRIN2B (0.39) PTPN7DUSP3KDM1AUSP28USP25
SCHEMBL29465742 0.82 GRIN2B (0.39) PTPN7DUSP3KDM1AUSP28USP25
SCHEMBL56867 0.81 CYP11B2 (0.53) KDM1ACYP11B1CYP11B2DGAT1
SCHEMBL29514712 0.81 CYP11B2 (0.53) KDM1ACYP11B1CYP11B2DGAT1
SCHEMBL23003727 0.80 KDM1A (0.36) PTPN7DUSP3KDM1AUSP28USP25
SCHEMBL6267032 0.80 KDM1A (0.50) KDM1ACYP11B1CYP11B2RXRAHCAR1
SCHEMBL30864218 0.80 KDM1A (0.50) KDM1ACYP11B1CYP11B2RXRAHCAR1
SCHEMBL3527105 0.79 PTGDR2 (0.42) PTPN7DUSP3KDM1ARXRAGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 489 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3543319-A1 METHOD OF MARKING HYDROCARBON LIQUIDS Johnson Matthey Public Limited Company (GB) 2019-09-25 EP claimed
US-20140120626-A1 METHOD OF MARKING HYDROCARBON LIQUIDS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2014-05-01 US claimed
EP-2707465-A1 METHOD OF MARKING HYDROCARBON LIQUIDS Johnson Matthey Public Limited Company (GB) 2014-03-19 EP claimed
WO-2012153132-A1 METHOD OF MARKING HYDROCARBON LIQUIDS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2012-11-15 WO claimed
CN-122079945-A Coumarin derivative containing substituted phenyl ether structure, preparation method and application thereof 2026-05-26 CN disclosed
US-12630534-B2 1-((1H-pyrazol-4-yl)methyl)-3-(phenyl)-1,3-dihydro-2H-imidazol-2-one derivatives and related compounds as GPR139 antagonists for the treatment of e.g. depression TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-05-19 US disclosed
EP-4698517-A1 <SUP2/>? <SUB2/>?4?NOVEL COMPOUNDS AS ?? <NS1:SUB>7</NS1:SUB>?INHIBITORS Evotec International GmbH (DE) 2026-02-25 EP disclosed
EP-4692089-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AS AAK1 INHIBITOR Alicorn Pharmaceutical Co., Ltd. (CN) 2026-02-11 EP disclosed
CN-121045488-A Wave-transparent resin for aircraft equipment cabin and preparation method thereof 江苏柯鲁威新材料科技有限公司 2025-12-02 CN disclosed
US-12479818-B2 Treatment of fibrosis with IRE1 small molecule inhibitors CORNELL UNIVERSITY (US) 2025-11-25 US disclosed
US-12435040-B2 1,3-substituted cyclobutyl derivatives and uses thereof BAUSCH + LOMB IRELAND LIMITED (IE) 2025-10-07 US disclosed
US-12427153-B2 1,2,4-triazin-3(2H)-one compounds for the treatment of hyperproliferative diseases BAYER AKTIENGESELLSCHAFT (DE) 2025-09-30 US disclosed
US-5696133-A ADMINISTERING COMPOUND WHICH MODULATES ACTIVITY OF PROGESTERONE RECEPTOR LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-12-09 US disclosed
US-5693646-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-12-02 US disclosed
US-5693647-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-12-02 US disclosed
US-5688808-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-11-18 US disclosed
US-5688810-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-11-18 US disclosed
EP-0800519-A1 STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS, INC. (US) 1997-10-15 EP disclosed
WO-1996019458-A2 STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS INCORPORATED (US) 1996-06-27 WO disclosed
US-3947460-A SEDATIVES-HYPNOTIC, TRANQUILIZER SANDOZ, INC. (US) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435040-B2 1,3-substituted cyclobutyl derivatives and uses thereof TRPV1, TRPV3, TRPV2 PTPN7 3329/4885DUSP3 2963/4885KDM1A 4513/4885
US-12427153-B2 1,2,4-triazin-3(2H)-one compounds for the treatment of hyperproliferative diseases CCNA1, CCNA2, CCNT2 PTPN7 1403/4885DUSP3 1879/4885KDM1A 1110/4885
US-12479818-B2 Treatment of fibrosis with IRE1 small molecule inhibitors XBP1, DDIT3, HSP90B1 PTPN7 3059/4885DUSP3 676/4885KDM1A 3328/4885
US-12630534-B2 1-((1H-pyrazol-4-yl)methyl)-3-(phenyl)-1,3-dihydro-2H-imidazol-2-one derivatives and related compounds as GPR139 antagonists for the treatment of e.g. depression GPR139, OPRL1, GRIN2C PTPN7 1353/4885DUSP3 2313/4885KDM1A 2503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.