SCHEMBL29516631

SCHEMBL29516631

Oc1c(CBr)cc(F)cc1CBr

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
ERN1 O75460 1/20 0.32
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
PTPN1 P18031 1/20 0.31
MEN1 O00255 2/20 0.31
ALDH1A1 P00352 2/20 0.31
POLB P06746 2/20 0.31
MAPT P10636 2/20 0.31
KMT2A Q03164 2/20 0.31
PLEC Q15149 1/20 0.31
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30
KDM4E B2RXH2 1/20 0.30
THRB P10828 1/20 0.30
APEX1 P27695 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22543122 0.81 TRPA1 (0.33) PTPN1ALDH1A1GABRA1GABRB2KDM4E
SCHEMBL21437010 0.78 BACE1 (0.39) CA12CA1CA9PTGS2PTPN1
SCHEMBL1057960 0.76 KDM4E (0.43) CA12CA1CA9ERN1PTGS1
SCHEMBL6443715 0.74 AMY1A (0.48) CA1ERN1ALDH1A1POLBMAPT
SCHEMBL29516784 0.74 HIF1A (0.48) ERN1MEN1ALDH1A1POLBMAPT
SCHEMBL11336230 0.74 CA12 (0.39) CA12CA1CA9ERN1PTGS1
SCHEMBL6912849 0.73 CA3 (0.44) CA9PTPN1MEN1ALDH1A1POLB
Bromide SCHEMBL6440480 0.72 HIF1A (0.47) ERN1MEN1ALDH1A1POLBMAPT
SCHEMBL489929 0.72 RIPK1 (0.41)
SCHEMBL4168914 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113024787-B Method for catalyzing ring-opening polymerization of epsilon-caprolactone by using [ OSSO ] type complex 河北工业大学 2022-05-10 CN claimed
CN-113024787-B Method for catalyzing ring-opening polymerization of epsilon-caprolactone by using [ OSSO ] type complex 河北工业大学 2022-05-10 CN disclosed