Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5789460 | 0.84 | ALDH1A1 (0.49) | LMNAALDH1A1CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL29671348 | 0.80 | ALDH1A1 (0.61) | LMNAALDH1A1ALOX15CYP2C9CYP2C19 | |
| SCHEMBL228778 | 0.80 | ALDH1A1 (0.61) | LMNAALDH1A1ALOX15CYP2C9CYP2C19 | |
| SCHEMBL7441090 | 0.79 | ALDH1A1 (0.50) | LMNAALDH1A1ALOX15CYP2C9CYP2C19 | |
| Lithium SCHEMBL31310856 | 0.79 | ALDH1A1 (0.59) | LMNAALDH1A1ALOX15CYP2C9CYP2C19 | |
| SCHEMBL7773542 | 0.78 | G6PD (0.53) | LMNAALDH1A1ALOX15CYP2C9CYP2C19 | |
| SCHEMBL11173849 | 0.78 | MYC (0.51) | LMNAALDH1A1ALOX15CYP2C9CYP2C19 | |
| SCHEMBL336107 | 0.77 | ALDH1A1 (0.60) | ALDH1A1ALOX15ALBPOLBKDM4E | |
| SCHEMBL30740619 | 0.75 | TTR (0.58) | ALDH1A1ALOX15ALBMRGPRX4TTR | |
| SCHEMBL22045254 | 0.74 | TP53 (0.53) | ALDH1A1ALOX15CYP2C9CYP2C19ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3965893-A1 | NEW THERAPEUTIC VECTORS AND PRODRUGS FOR TREATING CANCERS | Seekyo (FR) | 2022-03-16 | — | — | EP | disclosed |