Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | OGA | O60502 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919018 | 0.89 | THRB (0.51) | POLBOGAKDM4EALDH1A1HPGD | |
| SCHEMBL28919038 | 0.84 | CNR1 (0.47) | POLBOGAALDH1A1MAPTLMNA | |
| SCHEMBL18003469 | 0.78 | MAPT (0.58) | POLBOGAALDH1A1HPGDMAPT | |
| SCHEMBL10466693 | 0.78 | OGA (0.56) | POLBOGAALDH1A1HPGDMAPT | |
| SCHEMBL7185606 | 0.77 | ALDH1A1 (0.62) | POLBOGAKDM4EALDH1A1HPGD | |
| SCHEMBL29519544 | 0.77 | PCSK9 (0.50) | POLBALDH1A1MAPTLMNATHRB | |
| SCHEMBL28599298 | 0.77 | PCSK9 (0.50) | POLBALDH1A1MAPTLMNATHRB | |
| SCHEMBL28919053 | 0.76 | MAPT (0.61) | POLBALDH1A1MAPTLMNATHRB | |
| SCHEMBL10464669 | 0.76 | ALDH1A1 (0.64) | POLBOGAKDM4EALDH1A1HPGD | |
| SCHEMBL1118526 | 0.76 | OGA (0.54) | POLBOGAALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |