SCHEMBL29519902

SCHEMBL29519902

CCCC[C@H](NC(=O)[C@H](N)CC(C)C)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)O

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 7/20 0.61
MMP8 P22894 6/20 0.61
MMP1 P03956 4/20 0.61
MMP9 P14780 4/20 0.56
ERAP2 Q6P179 2/20 0.55
CCKAR P32238 2/20 0.55
CCKBR P32239 2/20 0.55
OPRD1 P41143 1/20 0.55
MMP7 P09237 1/20 0.55
ECE1 P42892 5/20 0.55
IL1RN P18510 1/20 0.52
ERAP1 Q9NZ08 1/20 0.52
NPY1R P25929 1/20 0.52
NPY2R P49146 1/20 0.52
NPY4R P50391 1/20 0.52
KISS1R Q969F8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30051322 0.92 ECE1 (0.64) MMP2MMP8MMP1MMP9ERAP2
SCHEMBL29519964 0.92 MMP2 (0.55) MMP2MMP8MMP1MMP9ERAP2
SCHEMBL29519671 0.90 ECE1 (0.65) MMP2MMP8MMP1ERAP2CCKAR
SCHEMBL22366982 0.90 ERAP2 (0.67) MMP2MMP8MMP1MMP9ERAP2
SCHEMBL29519586 0.89 MMP2 (0.52) MMP2MMP8MMP1MMP9ERAP2
SCHEMBL29872607 0.89 OPRM1 (0.62) MMP2MMP8MMP1MMP9ERAP2
SCHEMBL29794167 0.89 OPRM1 (0.62) MMP2MMP8MMP1MMP9ERAP2
SCHEMBL29520101 0.88 ECE1 (0.60) ERAP2CCKARCCKBROPRD1ECE1
SCHEMBL29519590 0.86 ERAP2 (0.55) MMP2MMP8MMP1MMP9ERAP2
SCHEMBL30052459 0.85 ECE1 (0.61) MMP2MMP8MMP1MMP9ERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4211146-B1 SYNTHETIC CYCLIC PEPTIDE MIMETICS UNIV BAR ILAN (IL) 2026-05-20 EP claimed
US-12616760-B2 Synthetic cyclic peptide mimetics BAR ILAN UNIVERSITY (IL) 2026-05-05 US claimed
US-20240316225-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS BAR ILAN UNIVERSITY (IL) 2024-09-26 US claimed
EP-4211146-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS Bar Ilan University (IL) 2023-07-19 EP claimed
WO-2022054062-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS BAR ILAN UNIVERSITY (IL) 2022-03-17 WO claimed
US-12616760-B2 Synthetic cyclic peptide mimetics BAR ILAN UNIVERSITY (IL) 2026-05-05 US disclosed
US-20240316225-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS BAR ILAN UNIVERSITY (IL) 2024-09-26 US disclosed
EP-4211146-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS Bar Ilan University (IL) 2023-07-19 EP disclosed
WO-2022054062-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS BAR ILAN UNIVERSITY (IL) 2022-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616760-B2 Synthetic cyclic peptide mimetics TPX2, IAPP, HAX1 MMP2 3162/4885MMP8 2150/4885MMP1 2143/4885
US-20240316225-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS IAPP, QPCTL, DNPEP MMP2 4037/4885MMP8 4022/4885MMP1 3415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.