Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | GALR3 | O60755 | 1/20 | 1.00 |
| ▸ | NR2F2 | P24468 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | ALPL | P05186 | 2/20 | 0.62 |
| ▸ | ALPI | P09923 | 1/20 | 0.62 |
| ▸ | ALPG | P10696 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15220623 | 0.91 | LMNA (0.83) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL9527642 | 0.87 | LMNA (0.77) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL9473989 | 0.81 | SMN1; SMN2 (0.68) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL2723205 | 0.81 | LMNA (0.68) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL10404013 | 0.81 | LMNA (0.67) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL9474003 | 0.79 | LMNA (0.64) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL9473521 | 0.78 | LMNA (0.63) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL15220621 | 0.78 | LMNA (0.64) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL9410392 | 0.78 | SMN1; SMN2 (0.62) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL9410436 | 0.77 | LMNA (0.61) | LMNASMN1; SMN2KMT2AGALR3NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220249436-A1 | Small Molecule Agonists and Antagonists of NR2F6 Activity in Humans | KCL THERAPEUTICS, INC (US) | 2022-08-11 | — | — | US | disclosed |
| US-11377442-B2 | Small molecule agonists and antagonists of NR2F6 activity | Zander Biologics, Inc (US) | 2022-07-05 | — | — | US | disclosed |
| US-11324719-B2 | Small molecule agonists and antagonists of NR2F6 activity in humans | KCL THERAPEUTICS, INC. (US) | 2022-05-10 | — | — | US | disclosed |
| US-11241427-B2 | Small molecule modulators of NR2F6 activity | KCL THERAPEUTICS, INC. (US) | 2022-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11241427-B2 | Small molecule modulators of NR2F6 activity | NR2F2, NR2E3, NR2C2 | LMNA 4730/4885SMN1; SMN2 2494/4885KMT2A 741/4885 |
| US-20220249436-A1 | Small Molecule Agonists and Antagonists of NR2F6 Activity in Humans | NR4A2, NR2C2, NR0B2 | LMNA 4829/4885SMN1; SMN2 2344/4885KMT2A 999/4885 |
| US-11324719-B2 | Small molecule agonists and antagonists of NR2F6 activity in humans | NR4A2, NR2C2, NR0B2 | LMNA 4829/4885SMN1; SMN2 2344/4885KMT2A 999/4885 |
| US-11377442-B2 | Small molecule agonists and antagonists of NR2F6 activity | NR4A2, NR2C2, NR2F2 | LMNA 4840/4885SMN1; SMN2 2982/4885KMT2A 968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.