Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.83 |
| ▸ | GALR3 | O60755 | 1/20 | 0.83 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.83 |
| ▸ | RAB9A | P51151 | 1/20 | 0.83 |
| ▸ | ALPL | P05186 | 2/20 | 0.64 |
| ▸ | ALPI | P09923 | 1/20 | 0.64 |
| ▸ | ALPG | P10696 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29520232 | 0.91 | LMNA (1.00) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL15220621 | 0.87 | LMNA (0.64) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL9527642 | 0.86 | LMNA (0.77) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL15220664 | 0.85 | LMNA (0.60) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL9473989 | 0.81 | SMN1; SMN2 (0.68) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL10404013 | 0.80 | LMNA (0.67) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL9474003 | 0.78 | LMNA (0.64) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL9473521 | 0.77 | LMNA (0.63) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL9410392 | 0.77 | SMN1; SMN2 (0.62) | LMNASMN1; SMN2KMT2AGALR3NR2F2 | |
| SCHEMBL9410436 | 0.76 | LMNA (0.61) | LMNASMN1; SMN2KMT2AGALR3NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2636669-B1 | PYRAZOLE AMIDE COMPOUND AND USE THEREOF AS FUNGICIDE | SINOCHEM CORP (CN) | 2015-10-21 | — | — | EP | disclosed |
| EP-2636669-A1 | PYRAZOLE AMIDE COMPOUND AND USE THEREOF | Sinochem Corporation (CN) | 2013-09-11 | — | — | EP | disclosed |
| US-20130225585-A1 | PYRAZOLE AMIDE COMPOUNDS AND USES THEREOF | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225585-A1 | PYRAZOLE AMIDE COMPOUNDS AND USES THEREOF | BROX, OAT, CAT | LMNA 4182/4885SMN1; SMN2 4315/4885KMT2A 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.