Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | RAB9A | P51151 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | GALR3 | O60755 | 1/20 | 0.77 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.77 |
| ▸ | ALPL | P05186 | 1/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.57 |
| ▸ | ALPG | P10696 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 11/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29520232 | 0.87 | LMNA (1.00) | LMNAKMT2ARAB9ASMN1; SMN2GALR3 | |
| SCHEMBL11938556 | 0.87 | LMNA (0.58) | LMNAKMT2ARAB9ASMN1; SMN2GALR3 | |
| SCHEMBL15220623 | 0.86 | LMNA (0.83) | LMNAKMT2ARAB9ASMN1; SMN2GALR3 | |
| SCHEMBL11938558 | 0.86 | LMNA (0.57) | LMNAKMT2ARAB9ASMN1; SMN2GALR3 | |
| Tebufenpyrad SCHEMBL8407688 | 0.86 | LMNA (0.59) | LMNAKMT2ARAB9ASMN1; SMN2GALR3 | |
| Tebufenpyrad SCHEMBL26848 | 0.86 | LMNA (0.59) | LMNAKMT2ARAB9ASMN1; SMN2GALR3 | |
| SCHEMBL20968008 | 0.86 | LMNA (0.57) | LMNAKMT2ARAB9ASMN1; SMN2GALR3 | |
| SCHEMBL9232030 | 0.85 | LMNA (0.56) | LMNAKMT2ARAB9ASMN1; SMN2GALR3 | |
| SCHEMBL19185689 | 0.85 | LMNA (0.56) | LMNAKMT2ARAB9ASMN1; SMN2GALR3 | |
| SCHEMBL11938496 | 0.84 | LMNA (0.72) | LMNAKMT2ARAB9ASMN1; SMN2GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289879-B1 | PYRAZOLE DERIVATIVE, INSECTICIDAL OR MITICIDAL COMPOSITION CONTAINING THE SAME AS THE EFFECTIVE INGREDIENT | MITSUBISHI KASEI CORPORATION (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4950668-A | Pyrazole derivative, insecticidal or miticidal composition containing the same as the effective ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1990-08-21 | — | — | US | disclosed |
| EP-0289879-A1 | Pyrazole derivative, insecticidal or miticidal composition containing the same as the effective ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1988-11-09 | — | — | EP | disclosed |