SCHEMBL29520274

SCHEMBL29520274

CCOC(OCC)c1ccc(Br)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 7/20 0.39
ACHE P22303 6/20 0.39
BCHE P06276 5/20 0.39
RAB9A P51151 4/20 0.39
ALDH1A1 P00352 3/20 0.39
KMT2A Q03164 2/20 0.39
S1PR1 P21453 1/20 0.34
NPC1 O15118 2/20 0.33
PKM P14618 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.31
HAO1 Q9UJM8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11061904 1.00 PTGS2 (0.39) PTGS2ACHEBCHERAB9AALDH1A1
SCHEMBL1280729 0.80 PTGS2 (0.38) PTGS2ACHEBCHERAB9ANPC1
SCHEMBL5377796 0.78 ESR1 (0.44) PTGS2ACHEBCHE
SCHEMBL11244312 0.76 SLC6A2 (0.43) PTGS2ACHEBCHEALDH1A1
SCHEMBL570123 0.76 ACHE (0.38) PTGS2ACHEBCHERAB9AALDH1A1
SCHEMBL508188 0.76 PTGS2 (0.50) PTGS2ACHEBCHERAB9AKMT2A
SCHEMBL6394314 0.75 PTGS2 (0.57) PTGS2ACHEBCHERAB9ANPC1
SCHEMBL9721323 0.74 PTGS2 (0.49) PTGS2ACHEBCHERAB9AKMT2A
SCHEMBL3141582 0.72 IDO1 (0.43) PTGS2ACHEBCHEALDH1A1
SCHEMBL31175995 0.72 IDO1 (0.43) PTGS2ACHEBCHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113387982-B Methyl-modified cage-type phosphorus ligand, preparation method and application thereof 东莞理工学院 2022-04-19 CN disclosed