SCHEMBL29520891

SCHEMBL29520891

O=C(O)Oc1ccccc1CC(F)F

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40
KMT2A Q03164 2/20 0.40
CXCL8 P10145 2/20 0.39
PPARA Q07869 2/20 0.38
PPARG P37231 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CTNNB1 P35222 1/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL609924 1.00 TSHR (0.40) TSHRKMT2ACXCL8PPARAPPARG
SCHEMBL609923 0.87 HPGD (0.40) TSHRKMT2ACXCL8PPARAPPARG
SCHEMBL5589414 0.85 GABRA1 (0.38) TSHRKMT2ACXCL8PPARAPPARG
SCHEMBL28396369 0.82 GABRA1 (0.46) TSHRKMT2AL3MBTL1KDM4EHPGD
SCHEMBL609669 0.82 CXCL8 (0.42) TSHRKMT2ACXCL8PPARAPPARG
SCHEMBL29521383 0.82 CXCL8 (0.42) TSHRKMT2ACXCL8PPARAPPARG
SCHEMBL611228 0.79 CXCL8 (0.42) TSHRKMT2ACXCL8L3MBTL1KDM4E
SCHEMBL4386559 0.79 ALDH1A1 (0.40) TSHRKMT2AL3MBTL1CYP1A2CYP2C9
SCHEMBL10338678 0.79 TSHR (0.41) TSHRKMT2ACXCL8L3MBTL1CYP2C9
SCHEMBL6006352 0.79 HTR1A (0.46) TSHRCXCL8L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110212235-B Lithium secondary battery electrolyte capable of reducing battery impedance and lithium secondary battery thereof 广州天赐高新材料股份有限公司 2022-04-08 CN disclosed