Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29524144 | 0.87 | KDM4E (0.38) | L3MBTL1KDM4ABRD4CREBBPLMNA | |
| SCHEMBL30571590 | 0.81 | L3MBTL1 (0.36) | PIM1PIM2L3MBTL1KDM4ABRD4 | |
| SCHEMBL29523623 | 0.76 | CA1 (0.36) | L3MBTL1KDM4ALMNAKDM4ECA1 | |
| SCHEMBL30571964 | 0.74 | KDM4E (0.39) | L3MBTL1KDM4ALMNAKDM4EPRMT5 | |
| SCHEMBL29523059 | 0.74 | HTT (0.38) | L3MBTL1KDM4ALMNAKDM4ECA1 | |
| SCHEMBL29761421 | 0.70 | CRBN (0.51) | DDB1CRBN | |
| SCHEMBL27153587 | 0.68 | ALDH1A1 (0.45) | PIM1CDC7DBF4L3MBTL1PARP1 | |
| SCHEMBL2048612 | 0.67 | GPR119 (0.46) | L3MBTL1KDM4ABRD4CREBBPPARP1 | |
| SCHEMBL30571536 | 0.67 | CA1 (0.37) | L3MBTL1KDM4ALMNAKDM4ECA1 | |
| SCHEMBL31351705 | 0.65 | PARP11 (0.49) | BRD4CREBBPCA1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4216946-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022066774-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2022-03-31 | — | — | WO | disclosed |