Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.73 |
| ▸ | NPC1 | O15118 | 7/20 | 0.73 |
| ▸ | RAB9A | P51151 | 7/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | HTT | P42858 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12238024 | 0.93 | SMN1; SMN2 (0.72) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL12941628 | 0.85 | ADORA2A (0.62) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL12238004 | 0.85 | PPARG (0.64) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL12238026 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL12238005 | 0.79 | PPARG (0.67) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL29365787 | 0.77 | RAB9A (0.67) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL29395943 | 0.77 | NPC1 (0.78) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL470778 | 0.77 | NPC1 (0.78) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL10562034 | 0.75 | PPARG (0.75) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL1276647 | 0.74 | INSR (0.46) | SMN1; SMN2ALDH1A1KMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11278525-B1 | Further molecules, compositions and methods for modulation of SIRT6 | SirTLab Corporation (IL) | 2022-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11278525-B1 | Further molecules, compositions and methods for modulation of SIRT6 | SIRT6, SIRT1, SIRT2 | SMN1; SMN2 2708/4885NPC1 1097/4885RAB9A 1219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.