Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.61 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.61 |
| ▸ | KDM5C | P41229 | 6/20 | 0.61 |
| ▸ | KDM5A | P29375 | 6/20 | 0.61 |
| ▸ | KDM4A | O75164 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.61 |
| ▸ | KDM3A | Q9Y4C1 | 4/20 | 0.61 |
| ▸ | KDM6B | O15054 | 3/20 | 0.61 |
| ▸ | TET3 | O43151 | 1/20 | 0.61 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | ASPH | Q12797 | 1/20 | 0.61 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.61 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.61 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.61 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.61 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.61 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353289 | 1.00 | KDM4C (0.61) | KDM4CKDM5BKDM5CKDM5AKDM4A | |
| Hydrochloric Acid SCHEMBL1256781 | 0.98 | KDM4C (0.59) | KDM4CKDM5BKDM5CKDM5AKDM4A | |
| Hydrochloric Acid SCHEMBL11077926 | 0.98 | KDM4C (0.59) | KDM4CKDM5BKDM5CKDM5AKDM4A | |
| Tert-Butylamine SCHEMBL28094088 | 0.91 | GABRP (0.55) | KDM4CKDM5BKDM5CKDM5AKDM4A | |
| SCHEMBL30083787 | 0.86 | KDM4C (0.55) | KDM4CKDM5BKDM5CKDM5AKDM4A | |
| SCHEMBL28990167 | 0.85 | CYP2C9 (0.54) | KDM4CKDM5BKDM5CKDM5AKDM4A | |
| SCHEMBL3356107 | 0.84 | UHRF1 (0.50) | KDM4CKDM5BKDM5CKDM5AKDM4A | |
| Methyl Isonicotinate SCHEMBL30268553 | 0.83 | KDM4E (0.63) | KDM4CKDM5BKDM5CKDM5AKDM4A | |
| SCHEMBL28472665 | 0.83 | KDM5A (0.47) | KDM4CKDM5BKDM5CKDM5AKDM4A | |
| SCHEMBL363432 | 0.83 | UHRF1 (0.48) | KDM4CKDM5BKDM5CKDM5AKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12152014-B2 | Therapeutic compounds and compositions | eXlthera Pharmaceuticals, Inc. (US) | 2024-11-26 | — | — | US | disclosed |
| US-20240059670-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | Cadrenal Therapeutics, Inc. | 2024-02-22 | — | — | US | disclosed |
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| US-11691962-B2 | Therapeutic compounds and compositions | EXITHERA PHARMACEUTICALS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| US-20230133132-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-05-04 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-3983378-A1 | INHIBITORS OF INTEGRATED STRESS RESPONSE PATHWAY | Praxis Biotech LLC (US) | 2022-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240059670-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | KLK5, KLK2, KLKB1 | KDM4C 475/4885KDM5B 355/4885KDM5C 468/4885 |
| US-12152014-B2 | Therapeutic compounds and compositions | KLK5, KLK2, KLKB1 | KDM4C 475/4885KDM5B 355/4885KDM5C 468/4885 |
| US-20230133132-A1 | NAMPT MODULATORS | NAMPT, MC4R, SIRT1 | KDM4C 3730/4885KDM5B 3355/4885KDM5C 3980/4885 |
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | KDM4C 4071/4885KDM5B 3452/4885KDM5C 4291/4885 |
| US-11691962-B2 | Therapeutic compounds and compositions | KLK5, KLK2, KLKB1 | KDM4C 475/4885KDM5B 355/4885KDM5C 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.