SCHEMBL3356107

SCHEMBL3356107

Cc1cc(C(=O)c2ccnc(C)c2)ccn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UHRF1 Q96T88 1/20 0.50
PROKR1 Q8TCW9 2/20 0.43
SMARCA2 P51531 1/20 0.43
SMARCA4 P51532 1/20 0.43
CCR9 P51686 1/20 0.43
HDAC3 O15379 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
ALDH1A1 P00352 2/20 0.42
KDM5A P29375 2/20 0.42
KDM4C Q9H3R0 2/20 0.42
KDM5B Q9UGL1 2/20 0.42
KDM4E B2RXH2 1/20 0.42
KDM6B O15054 1/20 0.42
TET3 O43151 1/20 0.42
KDM4A O75164 1/20 0.42
BBOX1 O75936 1/20 0.42
MAPT P10636 1/20 0.42
KDM5C P41229 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16139761 0.90 KMT2A (0.57) ALDH1A1KDM4CKDM4EKDM6BKDM4A
SCHEMBL29580893 0.84 UHRF1 (0.48) UHRF1PROKR1SMARCA2SMARCA4CCR9
SCHEMBL29527921 0.84 KDM4C (0.61) UHRF1ALDH1A1KDM5AKDM4CKDM5B
SCHEMBL353289 0.84 KDM4C (0.61) UHRF1ALDH1A1KDM5AKDM4CKDM5B
SCHEMBL363432 0.84 UHRF1 (0.48) UHRF1PROKR1SMARCA2SMARCA4CCR9
Hydrochloric Acid SCHEMBL11077926 0.83 KDM4C (0.59) UHRF1ALDH1A1KDM5AKDM4CKDM5B
SCHEMBL112539 0.83 CCNC (0.50) UHRF1PROKR1SMARCA2SMARCA4HDAC3
SCHEMBL829075 0.83 UHRF1 (0.46) UHRF1PROKR1SMARCA2SMARCA4CCR9
Hydrochloric Acid SCHEMBL1256781 0.83 KDM4C (0.59) UHRF1ALDH1A1KDM5AKDM4CKDM5B
SCHEMBL30100694 0.83 CCNC (0.50) UHRF1PROKR1SMARCA2SMARCA4HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3858877-B1 POLYFUNCTIONAL VINYL AROMATIC COPOLYMER AND METHOD FOR MANUFACTURING SAME, COPOLYMER RUBBER OBTAINED THEREFROM, RUBBER COMPOSITION, RUBBER CROSSLINKED MATERIAL, AND TIRE MEMBER NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2026-05-27 EP disclosed
US-20260071058-A1 MASTERBATCH FOR RUBBER MODIFICATION AND BRANCHED CONJUGATED DIENE POLYMER COMPOSITION ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-03-12 US disclosed
EP-4703396-A1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER Asahi Kasei Kabushiki Kaisha (JP) 2026-03-04 EP disclosed
EP-4703397-A1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-03-04 EP disclosed
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-02-26 US disclosed
EP-4570827-A1 CONJUGATED DIENE-BASED POLYMER, MOLDED BODY, PRODUCTION METHOD FOR CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND TIRE Asahi Kasei Kabushiki Kaisha (JP) 2025-06-18 EP disclosed
EP-3778654-B1 METHOD FOR PRODUCING CONJUGATED DIENE RUBBER ZEON CORP (JP) 2025-02-26 EP disclosed
WO-2025028621-A1 MODIFIED CONJUGATED DIENE POLYMER, BALE, METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, AND TIRE 旭化成株式会社 2025-02-06 WO disclosed
WO-2024225452-A1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER 旭化成株式会社 2024-10-31 WO disclosed
WO-2024225378-A1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER 旭化成株式会社 2024-10-31 WO disclosed
EP-2182028-B1 Rubber composition and tire SUMITOMO RUBBER IND (JP) 2012-12-12 EP disclosed
EP-2184318-A2 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-12 EP disclosed
EP-2182028-A1 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-05 EP disclosed
US-20100105826-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-29 US disclosed
US-20100099810-A1 POLYMER, RUBBER COMPOSITION AND TIRE USING THE SAME SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
US-20100099795-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
EP-2177562-A2 Polymer, rubber composition and tire using the same Sumitomo Rubber Industries, Ltd. (JP) 2010-04-21 EP disclosed
CN-101087891-A Treatment methods using bucindolol based on gene targeting UNIV COLORADO REGENTS (US) 2007-12-12 CN disclosed
CN-1127252-A Branched-amino-sbustituted thiazoles, processes for their preparation and the pharmaceutical compositions which contain them SANOFI SA (FR) 1996-07-24 CN disclosed
US-5017636-A Also containing polyisoprene, natural rubber, butadiene-styrene copolymer, wear and heat resistance, resilience JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071058-A1 MASTERBATCH FOR RUBBER MODIFICATION AND BRANCHED CONJUGATED DIENE POLYMER COMPOSITION COL1A1, TGFBR1, COL2A1 UHRF1 1951/4885PROKR1 3114/4885SMARCA2 597/4885
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire HMGB2, HMGB1, HMGB3 UHRF1 2798/4885PROKR1 1195/4885SMARCA2 569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.