Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4911470 | 0.73 | KMT2A (0.39) | CYP3A4CYP2D6CYP2C9SCN9AMEN1 | |
| SCHEMBL5988033 | 0.72 | SMN1; SMN2 (0.49) | MEN1ALDH1A1KMT2AGABRA5GABRB2 | |
| SCHEMBL17717276 | 0.72 | KMT2A (0.44) | MEN1ALDH1A1KMT2AGABRA5GABRB2 | |
| SCHEMBL2745279 | 0.72 | GABRA5 (0.46) | MEN1ALDH1A1KMT2AGABRA5GABRB2 | |
| SCHEMBL29528616 | 0.72 | MEN1 (0.35) | CYP3A4CYP2D6CYP2C9SCN9AMEN1 | |
| SCHEMBL11130654 | 0.70 | HSD17B10 (0.62) | MEN1ALDH1A1KMT2AGABRA5GABRB2 | |
| SCHEMBL13412495 | 0.70 | ALDH1A1 (0.38) | MEN1ALDH1A1KMT2AGABRA5GABRB2 | |
| SCHEMBL28883226 | 0.70 | KMT2A (0.38) | CYP3A4CYP2D6CYP2C9SCN9AMEN1 | |
| SCHEMBL17977280 | 0.69 | MEN1 (0.37) | CYP2D6CYP2C9MEN1ALDH1A1KMT2A | |
| SCHEMBL29528876 | 0.69 | ALDH1A1 (0.43) | CYP3A4MEN1ALDH1A1KMT2AGABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415358-B | 6-aminopyridin-3-ylthiazoles as ROR gamma t modulators | 詹森药业有限公司 | 2022-04-05 | — | — | CN | disclosed |