Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA9 | P38646 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29529344 | 1.00 | HSPA9 (0.53) | HSPA9ALDH1A1GRM5CASP3SENP8 | |
| SCHEMBL29528992 | 1.00 | HSPA9 (0.53) | HSPA9ALDH1A1GRM5CASP3SENP8 | |
| SCHEMBL20712728 | 0.82 | HSPA9 (0.60) | HSPA9ALDH1A1GRM5CASP3SENP8 | |
| SCHEMBL25753489 | 0.75 | ALDH1A1 (0.55) | HSPA9ALDH1A1GRM5CASP3SENP8 | |
| SCHEMBL19520791 | 0.73 | ALDH1A1 (0.49) | HSPA9ALDH1A1CASP3SENP8SENP7 | |
| SCHEMBL148962 | 0.72 | — | — | |
| SCHEMBL8592828 | 0.70 | — | — | |
| SCHEMBL29528940 | 0.70 | ALDH1A1 (0.49) | HSPA9ALDH1A1GRM5CASP3SENP8 | |
| SCHEMBL13101460 | 0.69 | HSPA9 (0.50) | HSPA9ALDH1A1CASP3SENP8SENP7 | |
| SCHEMBL28662188 | 0.69 | METAP1 (0.50) | HSPA9ALDH1A1CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415358-B | 6-aminopyridin-3-ylthiazoles as ROR gamma t modulators | 詹森药业有限公司 | 2022-04-05 | — | — | CN | disclosed |