Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28872364 | 1.00 | STS (0.46) | STSMAPTCHRM2CHRM4CHRM5 | |
| SCHEMBL29461449 | 0.78 | STS (0.45) | STSMAPTLMNAHTTKDM4E | |
| SCHEMBL5505983 | 0.73 | MAPT (0.58) | MAPTLMNAHTTNPSR1FLT3 | |
| SCHEMBL16872813 | 0.71 | MAPT (0.44) | MAPTLMNAHTTNPSR1BCHE | |
| SCHEMBL6433717 | 0.70 | ALOX5 (0.58) | MAPTKDM4EHSD17B10 | |
| SCHEMBL15009659 | 0.69 | LOXL2 (0.45) | MAPTLMNAHTTNPSR1LOXL2 | |
| SCHEMBL15064166 | 0.69 | HTT (0.53) | MAPTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL18115398 | 0.68 | CHRM2 (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL22720966 | 0.67 | CHRM2 (0.46) | MAPTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL29732524 | 0.67 | CHRM2 (0.46) | MAPTCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213370-B | Method for synthesizing alkylated electron-rich heterocyclic aromatic hydrocarbon by photo-induced NHPI ester decarboxylation coupling | 中山大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-114213370-A | Method for synthesizing alkylated electron-rich heterocyclic aromatic hydrocarbon by virtue of photoinduced decarboxylation coupling of NHPI ester | 中山大学 | 2022-03-22 | — | — | CN | disclosed |