Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25323757 | 1.00 | HTT (0.37) | HTTALOX5APFEN1FFAR1ALDH1A1 | |
| SCHEMBL25319653 | 0.84 | HTT (0.39) | HTTALOX5APFEN1FFAR1ALDH1A1 | |
| SCHEMBL4766847 | 0.84 | FFAR1 (0.45) | HTTFFAR1ALDH1A1SMN1; SMN2TGFBR1 | |
| SCHEMBL29529877 | 0.79 | LOXL2 (0.38) | RXRAGRIN1GRIN2BKCNH2 | |
| SCHEMBL25321602 | 0.79 | CLK1 (0.38) | HTTFFAR1ALDH1A1SMN1; SMN2NCOA3 | |
| SCHEMBL25320465 | 0.79 | LOXL2 (0.38) | RXRAGRIN1GRIN2BKCNH2 | |
| SCHEMBL29102328 | 0.78 | TGFBR1 (0.35) | TGFBR1RXRAGRIN1GRIN2B | |
| SCHEMBL25320336 | 0.77 | IDH1 (0.39) | HTTFFAR1ALDH1A1SMN1; SMN2NOTUM | |
| SCHEMBL25320659 | 0.76 | ALDH1A1 (0.38) | HTTALOX5APFEN1FFAR1ALDH1A1 | |
| SCHEMBL29530250 | 0.76 | ALDH1A1 (0.38) | HTTALOX5APFEN1FFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4217070-A1 | PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | Scorpion Therapeutics, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022066734-A1 | PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-03-31 | — | — | WO | disclosed |