Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | USP8 | P40818 | 1/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28711417 | 1.00 | ERN1 (0.42) | ERN1TDP1XDHS100A4HSD17B3 | |
| SCHEMBL8802386 | 0.81 | MEN1 (0.46) | TDP1XDHUSP8USP7ESR2 | |
| SCHEMBL6003472 | 0.81 | ERN1 (0.52) | ERN1TDP1XDHS100A4ALDH1A1 | |
| SCHEMBL10041701 | 0.78 | TDP1 (0.52) | ERN1TDP1XDHS100A4ALDH1A1 | |
| SCHEMBL584206 | 0.78 | ERN1 (0.52) | ERN1TDP1VCAM1ALDH1A1KDM4E | |
| SCHEMBL28711749 | 0.78 | ERN1 (0.46) | ERN1TDP1USP8ALDH1A1KDM4E | |
| SCHEMBL29532956 | 0.78 | ERN1 (0.46) | ERN1TDP1USP8ALDH1A1KDM4E | |
| SCHEMBL26635210 | 0.77 | XDH (0.47) | ERN1TDP1XDHHSD17B3VCAM1 | |
| SCHEMBL28533543 | 0.76 | ALDH1A1 (0.47) | ERN1TDP1XDHS100A4ALDH1A1 | |
| SCHEMBL11358448 | 0.74 | TDP1 (0.55) | ERN1TDP1VCAM1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276252-A | Method for preparing 9-amino-10-alkynyl phenanthrene ring derivative | 海南梵圣生物科技有限公司 | 2022-04-05 | — | — | CN | disclosed |