Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955194 | 0.84 | TDP1 (0.55) | ERN1TDP1VCAM1MAOAMAOB | |
| SCHEMBL11358448 | 0.84 | TDP1 (0.55) | ERN1TDP1VCAM1MAOAMAOB | |
| SCHEMBL26635210 | 0.80 | XDH (0.47) | ERN1TDP1VCAM1MAOAMAOB | |
| SCHEMBL16958095 | 0.80 | VCAM1 (0.44) | ERN1VCAM1MAOAMAOBGPR35 | |
| SCHEMBL22686751 | 0.80 | ERN1 (0.52) | ERN1TDP1VCAM1PTPN1HSD17B10 | |
| SCHEMBL16956740 | 0.80 | VCAM1 (0.44) | ERN1TDP1VCAM1MAOAMAOB | |
| SCHEMBL12352524 | 0.80 | VCAM1 (0.44) | TDP1VCAM1MAOAMAOBGPR35 | |
| SCHEMBL11485632 | 0.78 | AHR (0.45) | VCAM1MAOAMAOBGPR35CYP2A6 | |
| SCHEMBL11485637 | 0.78 | AHR (0.45) | VCAM1MAOAMAOBGPR35CYP2A6 | |
| SCHEMBL29531968 | 0.78 | ERN1 (0.42) | ERN1TDP1VCAM1GPR35HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382820-B | Synthetic method of 3-aryl isoindole derivative | Changzhou University (CN) | 2019-12-06 | — | — | CN | claimed |
| US-20260132112-A1 | COMPOUNDS | CTXT PTY LTD (AU) | 2026-05-14 | — | — | US | disclosed |
| EP-4077318-B1 | BENZIMIDAZOLE DIMERS AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2025-10-15 | — | — | EP | disclosed |
| US-12415785-B2 | Compound modulators of sting | CTXT PTY LTD (AU) | 2025-09-16 | — | — | US | disclosed |
| CN-114981265-B | Compounds of formula (I) | CTXT私人有限公司 | 2025-01-03 | — | — | CN | disclosed |
| US-20230062932-A1 | COMPOUNDS | CTXT PTY LTD. (AU) | 2023-03-02 | — | — | US | disclosed |
| US-20230062932-A1 | COMPOUNDS | CTXT PTY LTD. (AU) | 2023-03-02 | — | — | US | disclosed |
| WO-2022266711-A1 | SUBSTITUTED AMIDOBENZIMIDAZOLE DIMERS AS STING MODULATORS | Aculeus Therapeutics Pty Ltd (AU) | 2022-12-29 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-4077318-A1 | COMPOUNDS | CTXT PTY LTD (AU) | 2022-10-26 | — | — | EP | disclosed |
| CN-114981265-A | Compound (I) | CTXT私人有限公司 | 2022-08-30 | — | — | CN | disclosed |
| WO-2021119753-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2021-06-24 | — | — | WO | disclosed |
| CN-110627720-A | Synthesis method of 1-amino polysubstituted isoquinoline compound | 兰州大学 | 2019-12-31 | — | — | CN | disclosed |
| CN-107382820-B | Synthetic method of 3-aryl isoindole derivative | Changzhou University (CN) | 2019-12-06 | — | — | CN | disclosed |
| CN-108250127-A | A kind of preparation method of isoindoline ketone compound and its derivative | 陕西师范大学 | 2018-07-06 | — | — | CN | disclosed |
| US-20120077989-A1 | CYCLIC IMIDATE LIGANDS | UNIVERSITEIT GENT (BE) | 2012-03-29 | — | — | US | disclosed |
| EP-2416879-A1 | CYCLIC IMIDATE LIGANDS | Universiteit Gent (BE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010115903-A1 | CYCLIC IMIDATE LIGANDS | UNIVERSITEIT GENT (BE) | 2010-10-14 | — | — | WO | disclosed |
| US-4244966-A | 1,3-Dihydro-3-(2-hydroxy-, 2-bromo- or 2-chloroethyl)-2H-isoindol-1-one derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12415785-B2 | Compound modulators of sting | STING1, IRF3, MAVS | ERN1 681/4885TDP1 533/4885VCAM1 2507/4885 |
| US-20120077989-A1 | CYCLIC IMIDATE LIGANDS | IDH2, CYCS, NAPRT | ERN1 1168/4885TDP1 3931/4885VCAM1 4761/4885 |
| US-20260132112-A1 | COMPOUNDS | STING1, IRF3, CGAS | ERN1 669/4885TDP1 112/4885VCAM1 2109/4885 |
| US-20230062932-A1 | COMPOUNDS | STING1, IRF3, MAVS | ERN1 984/4885TDP1 404/4885VCAM1 1333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.