Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2383539 | 0.81 | — | — | |
| SCHEMBL29533582 | 0.81 | ROCK2 (0.31) | — | |
| SCHEMBL3391334 | 0.80 | POLB (0.35) | TSHRMAPT | |
| SCHEMBL539282 | 0.80 | POLB (0.35) | TSHRMAPT | |
| SCHEMBL28449146 | 0.73 | TSHR (0.34) | TSHRSLC18A3ARMAPT | |
| SCHEMBL1831745 | 0.71 | — | — | |
| SCHEMBL2384831 | 0.70 | TSHR (0.34) | TSHRSLC18A3ARMAPT | |
| O-Xylene SCHEMBL16581594 | 0.67 | TSHR (0.46) | TSHRMEN1KMT2A | |
| SCHEMBL20787645 | 0.66 | POLB (0.35) | TSHRMAPT | |
| SCHEMBL27768847 | 0.64 | HSP90AA1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4737444-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING MCL1 INHIBITORS | Gilead Sciences, Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| EP-3583088-B1 | SYNTHESIS OF PHEROMONES AND RELATED MATERIALS VIA OLEFIN METATHESIS | PROVIVI INC (US) | 2025-09-10 | — | — | EP | disclosed |
| US-12410146-B2 | Processes and intermediates for preparing MCL1 inhibitors | GILEAD SCIENCES, INC. (US) | 2025-09-09 | — | — | US | disclosed |
| US-20250179004-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING MCL1 INHIBITORS | GILEAD SCIENCES, INC. | 2025-06-05 | — | — | US | disclosed |
| US-12202782-B2 | Processes and intermediates for preparing MCL1 inhibitors | GILEAD SCIENCES, INC. (US) | 2025-01-21 | — | — | US | disclosed |
| EP-4484435-A2 | PROCESSES AND INTERMEDIATES FOR PREPARING MCL1 INHIBITORS | Gilead Sciences, Inc. (US) | 2025-01-01 | — | — | EP | disclosed |
| EP-4065567-B1 | PROCESSES AND INTERMEDIATES FOR PREPARING MCL1 INHIBITORS | GILEAD SCIENCES INC (US) | 2024-09-11 | — | — | EP | disclosed |
| US-20240285676-A1 | BOTTLEBRUSH POLYMERS AND METHODS THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2024-08-29 | — | — | US | disclosed |
| EP-4367109-A1 | PROCESS FOR PREPARING PERFUMING INTERMEDIATES | Firmenich SA (CH) | 2024-05-15 | — | — | EP | disclosed |
| US-11844353-B2 | Microorganisms for the production of insect pheromones and related compounds | PROVIVI, INC. (US) | 2023-12-19 | — | — | US | disclosed |
| WO-2023036732-A1 | PROCESS FOR PREPARING PERFUMING INTERMEDIATES | FIRMENICH SA (CH) | 2023-03-16 | — | — | WO | disclosed |
| US-20230013713-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING MCL1 INHIBITORS | GILEAD SCIENCES, INC. | 2023-01-19 | — | — | US | disclosed |
| WO-2022238774-A1 | MONOMER, POLYMERIZABLE COMPOSITION, AND POLYMERS DERIVED THEREFROM | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2022-11-17 | — | — | WO | disclosed |
| EP-4069667-A1 | PROCESS FOR PREPARING PERFUMING INTERMEDIATE | Firmenich SA (CH) | 2022-10-12 | — | — | EP | disclosed |
| EP-4065567-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING MCL1 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-05 | — | — | EP | disclosed |
| EP-4009966-A1 | SCALEABLE PREPARATION OF POLYKETIDES | The Regents of the University of California (US) | 2022-06-15 | — | — | EP | disclosed |
| US-20220177409-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING MCL1 INHIBITORS | GILEAD SCIENCES, INC. | 2022-06-09 | — | — | US | disclosed |
| WO-2022108984-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING MACROCYCLIC MCL1 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
| US-11325891-B2 | Processes and intermediates for preparing MCL1 inhibitors | GILEAD SCIENCES, INC. (US) | 2022-05-10 | — | — | US | disclosed |
| US-20220136018-A1 | SEMI-BIOSYNTHETIC PRODUCTION OF FATTY ALCOHOLS AND FATTY ALDEHYDES | HORIZON TECHNOLOGY FINANCE CORPORATION | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12410146-B2 | Processes and intermediates for preparing MCL1 inhibitors | MCL1, BAK1, BCL3 | TSHR 4596/4885SLC18A3 4701/4885AR 4219/4885 |
| US-20220177409-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING MCL1 INHIBITORS | MCL1, BCL3, XIAP | TSHR 4443/4885SLC18A3 4685/4885AR 4135/4885 |
| US-12202782-B2 | Processes and intermediates for preparing MCL1 inhibitors | MCL1, BCL3, XIAP | TSHR 4443/4885SLC18A3 4685/4885AR 4135/4885 |
| US-11844353-B2 | Microorganisms for the production of insect pheromones and related compounds | FASN, ACSL4, FADS1 | TSHR 1668/4885SLC18A3 3446/4885AR 959/4885 |
| US-20240285676-A1 | BOTTLEBRUSH POLYMERS AND METHODS THEREOF | PUF60, POLI, PUM1 | TSHR 3161/4885SLC18A3 4308/4885AR 4173/4885 |
| US-11325891-B2 | Processes and intermediates for preparing MCL1 inhibitors | MCL1, BAK1, BCL3 | TSHR 4596/4885SLC18A3 4701/4885AR 4219/4885 |
| US-20220136018-A1 | SEMI-BIOSYNTHETIC PRODUCTION OF FATTY ALCOHOLS AND FATTY ALDEHYDES | FASN, FAR1, COASY | TSHR 2273/4885SLC18A3 3724/4885AR 681/4885 |
| US-20250179004-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING MCL1 INHIBITORS | MCL1, BCL3, XIAP | TSHR 4443/4885SLC18A3 4685/4885AR 4135/4885 |
| US-20230013713-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING MCL1 INHIBITORS | MCL1, BAK1, BCL3 | TSHR 4596/4885SLC18A3 4701/4885AR 4219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.