SCHEMBL29535532

SCHEMBL29535532

O=S(=O)(O)N[C@H]1C(O)O[C@H](COS(=O)(=O)O)[C@@H](OS(=O)(=O)O)[C@@H]1O

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 2/20 0.48
▸ FGF1 P05230 3/20 0.43
▸ FGF2 P09038 2/20 0.43
▸ SERPINC1 P01008 2/20 0.37
▸ F2 P00734 1/20 0.37
▸ BDNF P23560 2/20 0.34
▸ PTN P21246 1/20 0.34
▸ MDK P21741 1/20 0.34
▸ SMPD1 P17405 2/20 0.32
▸ LGALS3 P17931 1/20 0.30
▸ HPSE Q9Y251 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29534894 0.89 F10 (0.43) F10FGF1FGF2SERPINC1F2
SCHEMBL29535345 0.86 LGALS3 (0.38) F10SERPINC1F2LGALS3
SCHEMBL1009127 0.85 F10 (0.42) F10FGF1FGF2SERPINC1F2
SCHEMBL20987120 0.85 F10 (0.42) F10FGF1FGF2SERPINC1F2
SCHEMBL7209912 0.85 F10 (0.42) F10FGF1FGF2SERPINC1F2
SCHEMBL16728926 0.85 F10 (0.42) F10FGF1FGF2SERPINC1F2
SCHEMBL13286928 0.85 F10 (0.42) F10FGF1FGF2SERPINC1F2
SCHEMBL21067663 0.85 F10 (0.42) F10FGF1FGF2SERPINC1F2
SCHEMBL7209918 0.85 F10 (0.42) F10FGF1FGF2SERPINC1F2
SCHEMBL16729027 0.83 F10 (0.41) F10FGF1FGF2SERPINC1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240366853-A1 METHOD FOR MODULATING ENDOTHELIAL GLYCOCALYX STRUCTURE EXTHERA MEDICAL CORPORATION (US) 2024-11-07 — — US disclosed
US-12090261-B2 Method for modulating endothelial glycocalyx structure EXTHERA MEDICAL CORPORATION (US) 2024-09-17 — — US disclosed
EP-3969014-A1 METHOD FOR MODULATING ENDOTHELIAL GLYCOCALYX STRUCTURE ExThera Medical Corporation (US) 2022-03-23 — — EP disclosed
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