SCHEMBL29534894

SCHEMBL29534894

O=S(=O)(O)N[C@H]1C(O)O[C@H](COS(=O)(=O)O)[C@@H](O)[C@@H]1OS(=O)(=O)O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 2/20 0.43
▸ FGF1 P05230 3/20 0.38
▸ FGF2 P09038 2/20 0.38
▸ SERPINC1 P01008 2/20 0.35
▸ F2 P00734 1/20 0.35
▸ LGALS3 P17931 1/20 0.32
▸ AMDHD2 Q9Y303 1/20 0.32
▸ HPSE Q9Y251 2/20 0.32
▸ CA2 P00918 1/20 0.31
▸ BDNF P23560 3/20 0.30
▸ PTN P21246 2/20 0.30
▸ MDK P21741 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29535532 0.89 F10 (0.48) F10FGF1FGF2SERPINC1F2
SCHEMBL16728933 0.86 MAPK1 (0.40) F10LGALS3CA2
SCHEMBL29535299 0.86 MAPK1 (0.40) F10LGALS3CA2
SCHEMBL7209912 0.85 F10 (0.42) F10FGF1FGF2SERPINC1F2
SCHEMBL21067663 0.85 F10 (0.42) F10FGF1FGF2SERPINC1F2
SCHEMBL13286928 0.85 F10 (0.42) F10FGF1FGF2SERPINC1F2
SCHEMBL16728926 0.85 F10 (0.42) F10FGF1FGF2SERPINC1F2
SCHEMBL20987120 0.85 F10 (0.42) F10FGF1FGF2SERPINC1F2
SCHEMBL7209918 0.85 F10 (0.42) F10FGF1FGF2SERPINC1F2
SCHEMBL1009127 0.85 F10 (0.42) F10FGF1FGF2SERPINC1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122012440-A Heparin 3-O-sulfate transferase mutant with high enzyme activity and high thermal stability, and encoding gene and application thereof 山东大学 2026-05-12 — — CN claimed
US-20250188506-A1 ANTICOAGULANT HEPARIN-CHONDROITIN CHIMERIC SACCHARIDE MOLECULE AS WELL AS PREPARATION METHOD AND APPLICATION THEREOF SHANDONG UNIVERSITY (CN) 2025-06-12 — — US claimed
CN-116622006-B Short acting heparin-based anticoagulant compounds and methods 北卡罗来纳大学查珀尔希尔分校 2025-05-30 — — CN claimed
CN-110446511-B Short acting heparin-based anticoagulant compounds and methods 北卡罗来纳大学查珀尔希尔分校 2024-04-02 — — CN claimed
WO-2024046048-A1 ANTICOAGULANT HEPARIN-DERIVED OLIGOSACCHARIDE BIPHENYL DIMER, AND PREPARATION METHOD THEREFOR AND USE THEREOF 山东大学 2024-03-07 — — WO claimed
US-20240066048-A1 SHORT-ACTING HEPARIN-BASED ANTICOAGULANT COMPOUNDS AND METHODS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2024-02-29 — — US claimed
US-11903963-B2 Short-acting heparin-based anticoagulant compounds and methods THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2024-02-20 — — US claimed
WO-2024032575-A1 HEPARIN DODECASACCHARIDE CONTAINING DOUBLE ANTITHROMBIN BINDING SEQUENCE, PREPARATION METHOD THEREFOR, AND USE THEREOF 山东大学 2024-02-15 — — WO claimed
CN-116622006-A Short acting heparin-based anticoagulant compounds and methods 北卡罗来纳大学查珀尔希尔分校 2023-08-22 — — CN claimed
CN-113583151-B Heparin molecules containing AT binding sequences and continuous 2-O-glucuronic acid residues, and preparation method and application thereof 山东大学 2023-06-20 — — CN claimed
CN-115417937-B Heparin dodecasaccharide containing double antithrombin binding sequence and preparation method and application thereof 山东大学 2023-06-06 — — CN claimed
WO-2023280235-A1 HEPARIN MOLECULE CONTAINING AT BINDING SEQUENCE AND CONTINUOUS 2-O-GLUCURONIC ACID RESIDUE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 山东大学 2023-01-12 — — WO claimed
US-20220404379-A1 SEQUENCING METHOD, SYSTEM AND KIT OF LOW MOLECULAR WEIGHT HEPARIN OLIGOSACCHARIDES SHANDONG UNIVERSITY (CN) 2022-12-22 — — US claimed
CN-113393904-B Method and system for detecting low-molecular heparin sugar chain sequence and sequencing kit 山东大学 2022-10-18 — — CN claimed
CN-111154819-B Non-animal source low molecular weight heparin and preparation method and application thereof 山东大学 2022-08-30 — — CN claimed
US-12636307-B2 In vitro heparin and heparan sulfate compositions and methods of making and using TEGA THERAPEUTICS, INC. (US) 2026-05-26 — — US disclosed
CN-122012440-A Heparin 3-O-sulfate transferase mutant with high enzyme activity and high thermal stability, and encoding gene and application thereof 山东大学 2026-05-12 — — CN disclosed
EP-4021461-A1 HEPARIN AND HEPARAN SULFATE FROM MODIFIED MST CELLS AND METHODS OF MAKING AND USING Tega Therapeutics, Inc. (US) 2022-07-06 — — EP disclosed
CN-109477829-B Nuclear magnetic resonance analysis method for glycosaminoglycan, heparin and derivatives thereof 罗维药物实验室股份有限公司 2022-06-21 — — CN disclosed
EP-3969014-A1 METHOD FOR MODULATING ENDOTHELIAL GLYCOCALYX STRUCTURE ExThera Medical Corporation (US) 2022-03-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11903963-B2 Short-acting heparin-based anticoagulant compounds and methods HPSE, STS, SULT1A1 F10 425/4885FGF1 1952/4885FGF2 1449/4885
US-20240066048-A1 SHORT-ACTING HEPARIN-BASED ANTICOAGULANT COMPOUNDS AND METHODS HPSE, STS, SULT1A1 F10 425/4885FGF1 1952/4885FGF2 1449/4885
US-12636307-B2 In vitro heparin and heparan sulfate compositions and methods of making and using TPST2, CSGALNACT1, B4GALT1 F10 3033/4885FGF1 1507/4885FGF2 761/4885
US-20250188506-A1 ANTICOAGULANT HEPARIN-CHONDROITIN CHIMERIC SACCHARIDE MOLECULE AS WELL AS PREPARATION METHOD AND APPLICATION THEREOF HPSE, CD44, CSGALNACT1 F10 46/4885FGF1 1060/4885FGF2 348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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