SCHEMBL7209918

SCHEMBL7209918

O=S(=O)(O)N[C@H]1[C@@H](O)[C@H](O)[C@@H](COS(=O)(=O)O)O[C@@H]1O

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 1/20 0.42
▸ AMDHD2 Q9Y303 1/20 0.40
▸ F2 P00734 1/20 0.37
▸ SERPINC1 P01008 1/20 0.37
▸ CA2 P00918 4/20 0.36
▸ FGF1 P05230 1/20 0.33
▸ FGF2 P09038 1/20 0.33
▸ HK2 P52789 5/20 0.32
▸ HK1 P19367 4/20 0.32
▸ FBP1 P09467 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ CYP2D6 P10635 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ CA12 O43570 3/20 0.30
▸ CA1 P00915 3/20 0.30
▸ CA9 Q16790 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13286928 1.00 F10 (0.42) F10AMDHD2F2SERPINC1CA2
SCHEMBL21067663 1.00 F10 (0.42) F10AMDHD2F2SERPINC1CA2
SCHEMBL20987120 1.00 F10 (0.42) F10AMDHD2F2SERPINC1CA2
SCHEMBL7209912 1.00 F10 (0.42) F10AMDHD2F2SERPINC1CA2
SCHEMBL1009127 1.00 F10 (0.42) F10AMDHD2F2SERPINC1CA2
SCHEMBL16728926 1.00 F10 (0.42) F10AMDHD2F2SERPINC1CA2
SCHEMBL15449484 0.87 F10 (0.36) F10AMDHD2F2SERPINC1CA2
SCHEMBL29535532 0.85 F10 (0.48) F10F2SERPINC1FGF1FGF2
SCHEMBL29534894 0.85 F10 (0.43) F10AMDHD2F2SERPINC1CA2
SCHEMBL17340086 0.82 F10 (0.57) F10SERPINC1CA2FGF1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2805930-B1 Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients CORNING INC (US) 2017-11-01 — — EP disclosed
US-9707155-B2 Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients CORNING INCORPORATED (US) 2017-07-18 — — US disclosed
US-20150140598-A1 Methods of Screening Sulfated Polysaccharides for Therapeutic Activity for a Glycocalyx-Related Disease DANIELS BRUCE A (US) 2015-05-21 — — US disclosed
EP-2805930-A1 Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients Corning Incorporated (US) 2014-11-26 — — EP disclosed
US-20140341891-A1 DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS CORNING INCORPORATED (US) 2014-11-20 — — US disclosed
EP-2766025-A1 THERAPEUTIC SULFATED POLYSACCHARIDES, COMPOSITIONS THEREOF, AND METHODS FOR TREATING PATIENTS Daniels, Bruce A. (US) 2014-08-20 — — EP disclosed
US-20140046052-A1 Therapeutic Sulfated Polysaccharides, Compositions Thereof, and Methods for Treating Patients DANIELS BRUCE A (US) 2014-02-13 — — US disclosed
US-20130273096-A1 Therapeutic Sulfated Polysaccharides, Compositions Thereof, and Methods for Treating Patients DANIELS BRUCE A (US) 2013-10-17 — — US disclosed
WO-2013052899-A1 THERAPEUTIC SULFATED POLYSACCHARIDES, COMPOSITIONS THEREOF, AND METHODS FOR TREATING PATIENTS DANIELS BRUCE A (US) 2013-04-11 — — WO disclosed
EP-0862581-B1 HEPARIN CHROMATOGRAPHY OF ERYTHROPOIETINS AVENTIS PHARMA INC (US) 2003-06-04 — — EP disclosed
US-6461844-B1 PHOSPHORYLATES N-ACETYLGALACTOSAMINE; FROM PIG KIDNEYS AND LIVERS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS 2002-10-08 — — US disclosed
EP-0862581-A1 HEPARIN CHROMATOGRAPHY OF ERYTHROPOIETINS HOECHST MARION ROUSSEL, INC. (US) 1998-09-09 — — EP disclosed
WO-1997017366-A1 HEPARIN CHROMATOGRAPHY OF ERYTHROPOIETINS HOECHST MARION ROUSSEL, INC. (US) 1997-05-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130273096-A1 Therapeutic Sulfated Polysaccharides, Compositions Thereof, and Methods for Treating Patients DDOST, CSGALNACT1, GYS2 F10 703/4885AMDHD2 1092/4885F2 511/4885
US-20140046052-A1 Therapeutic Sulfated Polysaccharides, Compositions Thereof, and Methods for Treating Patients DDOST, CSGALNACT1, GYS2 F10 703/4885AMDHD2 1092/4885F2 511/4885
US-20140341891-A1 DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS SIGLEC7, GYPA, NECTIN4 F10 1088/4885AMDHD2 3127/4885F2 3299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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