SCHEMBL7209912

SCHEMBL7209912

O=S(=O)(O)N[C@H]1C(O)O[C@H](COS(=O)(=O)O)[C@@H](O)[C@@H]1O

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 1/20 0.42
▸ AMDHD2 Q9Y303 1/20 0.40
▸ F2 P00734 1/20 0.37
▸ SERPINC1 P01008 1/20 0.37
▸ CA2 P00918 4/20 0.36
▸ FGF1 P05230 1/20 0.33
▸ FGF2 P09038 1/20 0.33
▸ HK2 P52789 5/20 0.32
▸ HK1 P19367 4/20 0.32
▸ FBP1 P09467 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ CYP2D6 P10635 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ CA12 O43570 3/20 0.30
▸ CA1 P00915 3/20 0.30
▸ CA9 Q16790 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13286928 1.00 F10 (0.42) F10AMDHD2F2SERPINC1CA2
SCHEMBL21067663 1.00 F10 (0.42) F10AMDHD2F2SERPINC1CA2
SCHEMBL7209918 1.00 F10 (0.42) F10AMDHD2F2SERPINC1CA2
SCHEMBL20987120 1.00 F10 (0.42) F10AMDHD2F2SERPINC1CA2
SCHEMBL1009127 1.00 F10 (0.42) F10AMDHD2F2SERPINC1CA2
SCHEMBL16728926 1.00 F10 (0.42) F10AMDHD2F2SERPINC1CA2
SCHEMBL15449484 0.87 F10 (0.36) F10AMDHD2F2SERPINC1CA2
SCHEMBL29535532 0.85 F10 (0.48) F10F2SERPINC1FGF1FGF2
SCHEMBL29534894 0.85 F10 (0.43) F10AMDHD2F2SERPINC1CA2
SCHEMBL17340086 0.82 F10 (0.57) F10SERPINC1CA2FGF1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122012440-A Heparin 3-O-sulfate transferase mutant with high enzyme activity and high thermal stability, and encoding gene and application thereof 山东大学 2026-05-12 — — CN claimed
US-12569512-B2 Heparan sulfate (HS) oligosaccharides effect in liver ischemia reperfusion injury THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2026-03-10 — — US claimed
WO-2025245431-A1 PREPARATION OF MEDIUM MOLECULAR WEIGHT HEPARIN GLYCOS BIOMEDICAL LTD (GB) 2025-11-27 — — WO claimed
WO-2025245445-A1 FUNCTIONALISED MEDIUM MOLECULAR WEIGHT HEPARIN GLYCOS BIOMEDICAL LTD (GB) 2025-11-27 — — WO claimed
EP-3672603-B1 COMBINATION OF A MAPK/ERK PATHWAY INHIBITOR AND A GLYCOSAMINOGLYCAN FOR THE TREATMENT OF CANCER Cell Receptor AG (CH) 2025-09-24 — — EP claimed
EP-4619446-A1 PREPARATION OF MEDIUM MOLECULAR WEIGHT HEPARIN Glycos Biomedical Ltd (GB) 2025-09-24 — — EP claimed
US-20250188506-A1 ANTICOAGULANT HEPARIN-CHONDROITIN CHIMERIC SACCHARIDE MOLECULE AS WELL AS PREPARATION METHOD AND APPLICATION THEREOF SHANDONG UNIVERSITY (CN) 2025-06-12 — — US claimed
WO-2025106117-A1 MEDIUM MOLECULAR WEIGHT HEPARIN Glycos Biomedical Ltd. (GB) 2025-05-22 — — WO claimed
CN-119375384-A Method for in-vitro detection of mucopolysaccharide and pompe disease related biomarker 浙江博圣生物技术股份有限公司 2025-01-28 — — CN claimed
US-20250019465-A1 COMPOSITIONS AND METHODS FOR RARE HEPARAN SULFATE GLYCAN-TARGETED CANCER TREATMENT THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-01-16 — — US claimed
US-11559544-B2 Combination of a MAPK/ERK pathway inhibitor and a glycosaminoglycan for the treatment of cancer Cell Receptor AG (CH) 2023-01-24 — — US claimed
WO-2023280235-A1 HEPARIN MOLECULE CONTAINING AT BINDING SEQUENCE AND CONTINUOUS 2-O-GLUCURONIC ACID RESIDUE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 山东大学 2023-01-12 — — WO claimed
US-20220404379-A1 SEQUENCING METHOD, SYSTEM AND KIT OF LOW MOLECULAR WEIGHT HEPARIN OLIGOSACCHARIDES SHANDONG UNIVERSITY (CN) 2022-12-22 — — US claimed
CN-115448994-A Neutralization anticoagulant low molecular weight heparin and preparation method and application thereof 山东大学 2022-12-09 — — CN claimed
CN-115417937-A Heparin decabiose containing double-antithrombin binding sequence and preparation method and application thereof 山东大学 2022-12-02 — — CN claimed
WO-2022238587-A1 MEDIUM MOLECULAR WEIGHT HEPARIN FOR USE IN THE TREATMENT OF ENDOTHELIOPATHY BHOGAL PERVINDER SINGH (GB) 2022-11-17 — — WO claimed
CN-113393904-B Method and system for detecting low-molecular heparin sugar chain sequence and sequencing kit 山东大学 2022-10-18 — — CN claimed
CN-111154819-B Non-animal source low molecular weight heparin and preparation method and application thereof 山东大学 2022-08-30 — — CN claimed
CN-114264741-B Method for identifying whether pig-derived heparin is doped with ruminant heparin 山东大学 2022-08-19 — — CN claimed
CN-114264741-A Method for identifying whether pig-derived heparin is doped with ruminant heparin 山东大学 2022-04-01 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569512-B2 Heparan sulfate (HS) oligosaccharides effect in liver ischemia reperfusion injury HPSE, GYS2, IRS1 F10 3709/4885AMDHD2 124/4885F2 2432/4885
US-20250188506-A1 ANTICOAGULANT HEPARIN-CHONDROITIN CHIMERIC SACCHARIDE MOLECULE AS WELL AS PREPARATION METHOD AND APPLICATION THEREOF HPSE, CD44, CSGALNACT1 F10 46/4885AMDHD2 338/4885F2 54/4885
US-20250019465-A1 COMPOSITIONS AND METHODS FOR RARE HEPARAN SULFATE GLYCAN-TARGETED CANCER TREATMENT HPSE, SDC4, SDC2 F10 2318/4885AMDHD2 90/4885F2 4225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback