Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5489083 | 1.00 | NUDT1 (0.42) | NUDT1ALDH1A1FGFR1HSP90AA1KDM4E | |
| SCHEMBL2408295 | 0.74 | RPS6KA5 (0.41) | ALDH1A1HSP90AA1KDM4ELMNAMEN1 | |
| SCHEMBL4143004 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HSP90AA1KDM4ELMNAMEN1 | |
| SCHEMBL22479754 | 0.74 | ALDH1A1 (0.41) | NUDT1ALDH1A1HSP90AA1KDM4ELMNA | |
| SCHEMBL29808133 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HSP90AA1KDM4ELMNAMEN1 | |
| SCHEMBL5794086 | 0.74 | PSMD14 (0.42) | NUDT1ALDH1A1HSP90AA1KDM4ELMNA | |
| SCHEMBL3001006 | 0.74 | KDM4E (0.44) | ALDH1A1HSP90AA1KDM4ELMNAMEN1 | |
| SCHEMBL10369050 | 0.74 | LMNA (0.61) | ALDH1A1HSP90AA1KDM4ELMNADHFR | |
| SCHEMBL7027758 | 0.72 | DYRK1A (0.57) | ALDH1A1HSP90AA1KDM4EMEN1KMT2A | |
| SCHEMBL2319759 | 0.71 | FGFR1 (0.42) | ALDH1A1FGFR1SRCDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612149-A1 | PYRIDO[2,3-D]PYRIMIDIN-2-AMINE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024094962-A1 | PYRIDO[2,3-D]PYRIMIDIN-2-AMINE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-05-10 | — | — | WO | disclosed |
| EP-4192582-A1 | KINASE INHIBITORS AND USES THEREOF | ABM Therapeutics Corporation (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032071-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORPORATION (US) | 2022-02-10 | — | — | WO | disclosed |