Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25274580 | 1.00 | LPL (0.33) | LPLLIPGCXCR2F2F11 | |
| SCHEMBL25422054 | 0.92 | LPL (0.33) | LPLLIPGCXCR2F2F11 | |
| SCHEMBL28239843 | 0.81 | ALDH1A1 (0.38) | ESR1ESR2 | |
| SCHEMBL2152374 | 0.78 | ESR1 (0.51) | ESR1ESR2 | |
| SCHEMBL29091787 | 0.77 | ESR1 (0.36) | ESR1ESR2 | |
| SCHEMBL442782 | 0.75 | ROCK1 (0.38) | LPLLIPGF2F11PRSS1 | |
| SCHEMBL25422045 | 0.75 | ESR1 (0.36) | ESR1ESR2 | |
| SCHEMBL29537290 | 0.75 | ESR1 (0.36) | ESR1ESR2 | |
| SCHEMBL24745880 | 0.74 | RXRA (0.33) | LPLLIPGCXCR2 | |
| SCHEMBL558091 | 0.74 | AGTR2 (0.41) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192582-A1 | KINASE INHIBITORS AND USES THEREOF | ABM Therapeutics Corporation (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032071-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORPORATION (US) | 2022-02-10 | — | — | WO | disclosed |