Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | TPO | P07202 | 1/20 | 0.50 |
| ▸ | EPX | P11678 | 1/20 | 0.50 |
| ▸ | LPO | P22079 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 10/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465571 | 1.00 | LTA4H (0.51) | LTA4HMPOTPOEPXLPO | |
| SCHEMBL29564176 | 0.85 | LTA4H (0.60) | LTA4HMPOTPOEPXLPO | |
| SCHEMBL28443559 | 0.84 | MAPT (0.57) | LTA4HMPOTPOEPXLPO | |
| SCHEMBL30086862 | 0.80 | MPO (0.47) | LTA4HMPOTPOEPXLPO | |
| SCHEMBL23888744 | 0.80 | MPO (0.47) | LTA4HMPOTPOEPXLPO | |
| SCHEMBL26013341 | 0.79 | ALDH1A1 (0.61) | LTA4HMPOTPOEPXLPO | |
| SCHEMBL5786732 | 0.78 | LTA4H (0.50) | LTA4H | |
| SCHEMBL1826466 | 0.78 | MAOA (0.56) | LTA4HMPOTPOEPXLPO | |
| SCHEMBL30876942 | 0.76 | LTA4H (0.51) | LTA4HMPOTPOEPXLPO | |
| SCHEMBL4470527 | 0.76 | CDK8 (0.56) | LTA4HMPOTPOEPXLPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214198-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | Hutchison Medipharma Limited (CN) | 2023-07-26 | — | — | EP | disclosed |
| CN-116323582-A | Heteroaromatic ring compounds and uses thereof | 和记黄埔医药（上海）有限公司 | 2023-06-23 | — | — | CN | disclosed |
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |