SCHEMBL29539536

SCHEMBL29539536

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nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 1/20 0.48
▸ ENPEP Q07075 17/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31432463 1.00 FOLH1 (0.48) FOLH1ENPEP
SCHEMBL29709563 0.96 FOLH1 (0.44) FOLH1ENPEP
SCHEMBL29391346 0.93 CTSD (0.44) FOLH1ENPEP
SCHEMBL30051366 0.91 ENPEP (0.49) ENPEP
SCHEMBL30053260 0.91 FOLH1 (0.42) FOLH1ENPEP
SCHEMBL30052717 0.91 ENPEP (0.47) FOLH1ENPEP
SCHEMBL30163257 0.90 ENPEP (0.51) FOLH1ENPEP
SCHEMBL31203047 0.89 FNTA (0.48) FOLH1ENPEP
SCHEMBL31614420 0.89 BACE1 (0.46) FOLH1ENPEP
SCHEMBL30051583 0.89 FOLH1 (0.51) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 — — US disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 — — US disclosed
US-20220340887-A1 Polymerases SEQULITE GENOMICS US INC (US) 2022-10-27 — — US disclosed
CN-114402067-A Polymerase enzyme 美国赛库莱特生物有限公司 2022-04-26 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP FOLH1 48/4885ENPEP 18/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD FOLH1 21/4885ENPEP 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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