SCHEMBL29539676

SCHEMBL29539676

Cc1cccc(N=Nc2ccc(N(C)C)cc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 8/20 1.00
▸ RAB9A P51151 7/20 1.00
▸ KMT2A Q03164 7/20 1.00
▸ MEN1 O00255 6/20 1.00
▸ TDP1 Q9NUW8 4/20 1.00
▸ CASP3 P42574 3/20 1.00
▸ SENP8 Q96LD8 3/20 1.00
▸ SENP7 Q9BQF6 3/20 1.00
▸ SENP6 Q9GZR1 3/20 1.00
▸ NSD2 O96028 1/20 1.00
▸ ALDH1A1 P00352 5/20 0.66
▸ MAPK1 P28482 4/20 0.66
▸ TSHR P16473 4/20 0.66
▸ HSD17B10 Q99714 2/20 0.66
▸ CA12 O43570 2/20 0.58
▸ CA2 P00918 2/20 0.58
▸ CA9 Q16790 2/20 0.58
▸ ALPL P05186 1/20 0.49
▸ ALPI P09923 1/20 0.49
▸ ALPG P10696 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL410348 1.00 NPC1 (1.00) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL410347 1.00 NPC1 (1.00) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL26712504 0.82 NPC1 (0.69) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL30471681 0.82 NPC1 (0.69) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL10814151 0.82 NPC1 (0.69) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL30332449 0.82 MEN1 (0.67) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL30102207 0.82 MEN1 (0.67) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL11981455 0.82 MEN1 (0.67) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL1405327 0.82 MEN1 (0.67) NPC1RAB9AKMT2AMEN1TDP1
SCHEMBL1405329 0.82 MEN1 (0.67) NPC1RAB9AKMT2AMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124324-A1 PHOTOCLICK CHEMISTRY OF SILK FOR TEMPORARY UV TATTOOS TUFTS COLLEGE (US) 2026-05-07 — — US disclosed
EP-4734896-A2 BIOPOLYMER-BASED TYMPANOSTOMY TUBES WITH PROGRAMMABLE, TUNABLE, AND ON-DEMAND DEGRADATION Trustees Of Tufts College (US) 2026-05-06 — — EP disclosed
EP-4735018-A2 CENTRIFUGALLY-MOLDED ARTICLES AND METHODS Trustees Of Tufts College (US) 2026-05-06 — — EP disclosed
US-20260114758-A1 PAPER-BASED WEARABLE PATCHES FOR REAL-TIME, QUANTITATIVE LACTATE MONITORING Trustees of Tuffs College (US) 2026-04-30 — — US disclosed
EP-4705404-A2 SILK-BASED ADHESIVE PLATFORM FOR FOOTWEAR AND FASHION Trustees Of Tufts College (US) 2026-03-11 — — EP disclosed
EP-4661753-A2 PAPER-BASED WEARABLE PATCHES FOR REAL-TIME, QUANTITATIVE LACTATE MONITORING Trustees Of Tufts College (US) 2025-12-17 — — EP disclosed
WO-2025227091-A1 IMPROVED WHIPPED SILK CREAMS AND METHODS OF MAKING AND USING THE SAME TRUSTEES OF TUFTS COLLEGE (US) 2025-10-30 — — WO disclosed
US-20250325495-A1 SILK NANOPARTICLE SYNTHESIS: TUNING SIZE, DISPERSITY, AND SURFACE CHEMISTRY FOR DRUG DELIVERY TUFTS COLLEGE (US) 2025-10-23 — — US disclosed
WO-2025217387-A1 SILK COATING OF MUSICAL INSTRUMENTS AND MUSICAL INSTRUMENT COMPONENTS AND ACCESSORIES TRUSTEES OF TUFTS COLLEGE (US) 2025-10-16 — — WO disclosed
WO-2025091012-A1 IMPROVED SILK LEATHER AND METHODS OF MAKING AND USING THE SAME TRUSTEES OF TUFTS COLLEGE (US) 2025-05-01 — — WO disclosed
WO-2024158919-A2 SILK BIOPLASTICS AND METHOD OF MAKING SAME TRUSTEES OF TUFTS COLLEGE (US) 2024-08-02 — — WO disclosed
WO-2024145272-A1 MODULAR BONE SCAFFOLD TRUSTEES OF TUFTS COLLEGE (US) 2024-07-04 — — WO disclosed
WO-2024097977-A1 SILK NANOPARTICLE SYNTHESIS: TUNING SIZE, DISPERSITY, AND SURFACE CHEMISTRY FOR DRUG DELIVERY TRUSTEES OF TUFTS COLLEGE (US) 2024-05-10 — — WO disclosed
US-20230302179-A1 MOVING-FRONT STERILIZATION MONITORING DEVICES SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-09-28 — — US disclosed
EP-4196181-A1 MOVING-FRONT STERILIZATION MONITORING DEVICES 3M Innovative Properties Company (US) 2023-06-21 — — EP disclosed
CN-116033930-A Mobile front edge sterilization monitoring device 3M创新有限公司 2023-04-28 — — CN disclosed
US-20220267621-A1 BIO-INK COMPOSITIONS, ENVIRONMENTALLY-SENSITIVE OBJECTS, AND METHODS OF MAKING THE SAME TRUSTEES OF TUFTS COLLEGE 2022-08-25 — — US disclosed
US-20220193305-A1 CROSSLINKED SILK FIBROIN-BASED COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME TRUSTEES OF TUFTS COLLEGE 2022-06-23 — — US disclosed
CN-107984936-B Reusable writing material and preparation method thereof 吉林大学 2022-05-06 — — CN disclosed
WO-2022034498-A1 MOVING-FRONT STERILIZATION MONITORING DEVICES 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-02-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260114758-A1 PAPER-BASED WEARABLE PATCHES FOR REAL-TIME, QUANTITATIVE LACTATE MONITORING LDHB, LDHA, LPO NPC1 4884/4885RAB9A 4516/4885KMT2A 3172/4885
US-20260124324-A1 PHOTOCLICK CHEMISTRY OF SILK FOR TEMPORARY UV TATTOOS PTMS, ITK, MATK NPC1 4479/4885RAB9A 1581/4885KMT2A 3435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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