Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2952186 | 0.89 | PRKCI (0.52) | PRKCIPRKCZHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL8084976 | 0.84 | EDNRB (0.50) | HSD17B10KDM4ESMN1; SMN2TP53HPGD | |
| SCHEMBL8081346 | 0.79 | NPC1 (0.48) | HSD17B10KDM4ESMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL22117121 | 0.79 | PRKCI (0.56) | PRKCIPRKCZHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL10049626 | 0.78 | MAPT (0.58) | PRKCIPRKCZHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL10018127 | 0.76 | PRKCI (0.53) | PRKCIPRKCZHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL8081905 | 0.74 | ALOX5 (0.45) | KDM4EHPGDALDH1A1EDNRBMAPK1 | |
| SCHEMBL9871276 | 0.74 | MEN1 (0.41) | HSD17B10KDM4ESMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL8084890 | 0.74 | EDNRA (0.45) | KDM4EHPGDALDH1A1L3MBTL1EDNRB | |
| SCHEMBL8085195 | 0.74 | MAPT (0.45) | HSD17B10KDM4ESMN1; SMN2TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080167353-A1 | Novel Antiviral Helioxanthin Analogs | YALE UNIVERSITY (US) | 2008-07-10 | — | — | US | claimed |
| WO-2005107742-A1 | NOVEL ANTIVIRAL HELIOXANTHIN ANALOGS | YALE UNIVERSITY (US) | 2005-11-17 | — | — | WO | claimed |
| US-7754718-B2 | Antiviral helioxanthin analogs | YALE UNIVERSITY (US) | 2010-07-13 | — | — | US | disclosed |
| US-20080167353-A1 | Novel Antiviral Helioxanthin Analogs | YALE UNIVERSITY (US) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167353-A1 | Novel Antiviral Helioxanthin Analogs | HAVCR2, ZC3HAV1, DHX35 | PRKCI 4078/4885PRKCZ 4412/4885HSD17B10 904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.