Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2954233 | 0.74 | PRKCI (0.49) | MEN1KMT2AL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL9871266 | 0.73 | MEN1 (0.42) | MEN1KMT2AL3MBTL1NPC1ATM | |
| SCHEMBL9327972 | 0.71 | LMNA (0.42) | MEN1KMT2AL3MBTL1NPC1ATM | |
| SCHEMBL2952186 | 0.70 | PRKCI (0.52) | L3MBTL1NPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL9860617 | 0.67 | SLC10A2 (0.48) | MEN1KMT2AL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL9860541 | 0.67 | TUBB4A (0.54) | MEN1KMT2AL3MBTL1NPC1ATM | |
| SCHEMBL9329585 | 0.67 | LMNA (0.39) | MEN1KMT2AL3MBTL1NPC1ATM | |
| SCHEMBL11367616 | 0.67 | ALDH1A1 (0.52) | MEN1KMT2AL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL9015832 | 0.67 | PDE3B (0.49) | KDM4EHSD17B10 | |
| SCHEMBL10049626 | 0.65 | MAPT (0.58) | MEN1KMT2ANPC1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011948-A | Cleavage of isoxazole rings, reduction to amine, cyclization, lactonization; anticarcinogenic agents | BRISTOL-MYERS COMPANY (US) | 1991-04-30 | — | — | US | disclosed |