Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 3/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29544663 | 0.76 | RIPK3 (0.36) | — | |
| SCHEMBL31440156 | 0.72 | HSP90AA1 (0.39) | BUB1POLBHSP90AA1HSP90AB1 | |
| SCHEMBL29544753 | 0.71 | CCNC (0.36) | PARP1PIM1PIM2 | |
| SCHEMBL29545041 | 0.71 | PIM1 (0.36) | MAPK1PIM1PIM2 | |
| SCHEMBL29544520 | 0.70 | USP7 (0.38) | PARP1 | |
| SCHEMBL29545095 | 0.70 | USP7 (0.41) | PARP1PIM1PIM2 | |
| SCHEMBL29544561 | 0.70 | MET (0.34) | — | |
| SCHEMBL29545167 | 0.70 | PIK3CA (0.32) | PARP1 | |
| SCHEMBL29544960 | 0.70 | PARP1 (0.32) | PARP1 | |
| SCHEMBL29544675 | 0.67 | PIK3CA (0.40) | BUB1POLBHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |