Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.32 |
| ▸ | CDK9 | P50750 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | TEK | Q02763 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29545041 | 0.90 | PIM1 (0.36) | NCF1SRCKDM4EMAPTMAPK1 | |
| SCHEMBL29545042 | 0.90 | PIM1 (0.36) | NCF1SRCKDM4EMAPTMAPK1 | |
| SCHEMBL29544955 | 0.84 | EGFR (0.39) | SRCKDM4EEGFRCCNT1CDK9 | |
| SCHEMBL29544881 | 0.84 | ATM (0.38) | NCF1MAPTEGFRCCNT1CDK9 | |
| SCHEMBL29544561 | 0.81 | MET (0.34) | NCF1METTGFBR1 | |
| SCHEMBL29545167 | 0.81 | PIK3CA (0.32) | TGFBR1 | |
| SCHEMBL29544572 | 0.81 | EGFR (0.40) | EGFRCCNT1CDK9METCSF1R | |
| SCHEMBL29544753 | 0.75 | CCNC (0.36) | TGFBR1 | |
| SCHEMBL29544635 | 0.74 | NCF1 (0.38) | NCF1SRCERBB2EGFRSYK | |
| SCHEMBL29544676 | 0.74 | NCF1 (0.38) | NCF1SRCERBB2EGFRSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |