Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.39 |
| ▸ | TYK2 | P29597 | 10/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29544745 | 0.93 | TYK2 (0.36) | TYK2CDK9RIPK3RORCTGFBR1 | |
| SCHEMBL29545531 | 0.89 | TYK2 (0.35) | EGFRTYK2CCNT1CDK9RORC | |
| SCHEMBL29544843 | 0.89 | FGFR1 (0.38) | EGFRTYK2CD274 | |
| SCHEMBL29544468 | 0.86 | EGFR (0.41) | EGFRTYK2CCNT1CDK9 | |
| SCHEMBL29544580 | 0.82 | TYK2 (0.37) | EGFRTYK2 | |
| SCHEMBL29544663 | 0.82 | RIPK3 (0.36) | EGFRCDK9RIPK3RORCTGFBR1 | |
| SCHEMBL29544700 | 0.82 | EGFR (0.40) | EGFRTYK2CCNT1CDK9 | |
| SCHEMBL29544572 | 0.81 | EGFR (0.40) | EGFRTYK2CCNT1CDK9CD274 | |
| SCHEMBL29545505 | 0.80 | IRAK4 (0.41) | TYK2RIPK3TGFBR1 | |
| SCHEMBL29545140 | 0.79 | EGFR (0.42) | EGFRTYK2TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |