Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20583909 | 1.00 | GAA (0.61) | GAAKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL20583911 | 1.00 | GAA (0.61) | GAAKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10806724 | 0.84 | RAB9A (0.55) | GAAKMT2ASMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL10805983 | 0.83 | L3MBTL1 (0.65) | GAAKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL21431899 | 0.82 | L3MBTL1 (0.55) | GAAKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10801436 | 0.81 | L3MBTL1 (0.54) | GAAKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL20583292 | 0.80 | GAA (0.71) | GAAKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9795955 | 0.80 | GAA (0.71) | GAAKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9795959 | 0.80 | GAA (0.71) | GAAKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL23515734 | 0.79 | GAA (0.69) | GAAKMT2ASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716381-A | Compounds useful as kinase inhibitors | 洛克索肿瘤学股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114634447-A | Compounds useful as kinase inhibitors | 洛克索肿瘤学股份有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114621146-A | Compounds useful as kinase inhibitors | 洛克索肿瘤学股份有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114605327-A | Compounds useful as kinase inhibitors | 洛克索肿瘤学股份有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-114591242-A | Compounds useful as kinase inhibitors | 洛克索肿瘤学股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114573510-A | Compounds useful as kinase inhibitors | 洛克索肿瘤学股份有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-108473481-B | Compounds useful as kinase inhibitors | 洛克索肿瘤学股份有限公司 | 2022-04-19 | — | — | CN | disclosed |