Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20581110 | 0.83 | L3MBTL1 (0.51) | L3MBTL1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL20581109 | 0.83 | L3MBTL1 (0.51) | L3MBTL1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL20583909 | 0.81 | GAA (0.61) | L3MBTL1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL20583911 | 0.81 | GAA (0.61) | L3MBTL1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL29544846 | 0.81 | GAA (0.61) | L3MBTL1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL9795932 | 0.81 | ALDH1A1 (0.56) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9795934 | 0.81 | ALDH1A1 (0.56) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL20581090 | 0.81 | L3MBTL1 (0.50) | L3MBTL1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL20581393 | 0.81 | L3MBTL1 (0.50) | L3MBTL1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL21431899 | 0.80 | L3MBTL1 (0.55) | L3MBTL1RAB9ANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214158-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-03-18 | — | — | EP | claimed |
| WO-1986004582-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1986-08-14 | — | — | WO | claimed |