SCHEMBL2954629

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28926584	0.89	TOP2A (0.59)	TOP2AMAPTNPC1RAB9AMEN1
	SCHEMBL206232	0.85	TOP2A (0.56)	TOP2AMAPTPTPRFPTPN2PTPN1
	SCHEMBL121325	0.84	TOP2A (0.65)	TOP2AMAPTNPC1RAB9AMEN1
	SCHEMBL16383496	0.83	TOP2A (0.54)	TOP2AMAPTPTPN1NPC1RAB9A
	SCHEMBL205351	0.82	TOP2A (0.53)	TOP2AMAPTRXFP1NPC1RAB9A
	SCHEMBL120321	0.82	HTR3A (0.54)	TOP2AMAPTPTPN2PTPN1CASP3
	SCHEMBL121392	0.82	HTR3A (0.54)	TOP2AMAPTPTPN2PTPN1NPC1
	SCHEMBL2957072	0.81	TOP2A (0.59)	TOP2AMAPTRXFP1PTPN2PTPN1
	SCHEMBL2961027	0.80	TOP2A (0.54)	TOP2AMAPTRXFP1NPC1RAB9A
	SCHEMBL27937347	0.79	NPC1 (0.48)	MAPTRXFP1PTPN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.