SCHEMBL29546820

SCHEMBL29546820

CO/C(=C\C=C\c1cc2cc(Cl)c(Cl)cc2[nH]1)C(=O)NC1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ATP6V1B1 P15313 5/20 0.80
ATP6AP1 Q15904 1/20 0.60
HDAC4 P56524 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1229725 1.00 ATP6V1B1 (0.80) ATP6V1B1ATP6AP1HDAC4HDAC6
SCHEMBL6296395 1.00 ATP6V1B1 (0.80) ATP6V1B1ATP6AP1HDAC4HDAC6
SCHEMBL6296361 1.00 ATP6V1B1 (0.80) ATP6V1B1ATP6AP1HDAC4HDAC6
SCHEMBL1229728 1.00 ATP6V1B1 (0.80) ATP6V1B1ATP6AP1HDAC4HDAC6
SCHEMBL1229727 1.00 ATP6V1B1 (0.80) ATP6V1B1ATP6AP1HDAC4HDAC6
SCHEMBL2400959 0.90 ATP6V1B1 (0.64) ATP6V1B1ATP6AP1HDAC4HDAC6
SCHEMBL2400947 0.90 ATP6V1B1 (0.64) ATP6V1B1ATP6AP1HDAC4HDAC6
SCHEMBL2400954 0.90 ATP6V1B1 (0.64) ATP6V1B1ATP6AP1HDAC4HDAC6
SCHEMBL6295642 0.86 ATP6V1B1 (0.59) ATP6V1B1ATP6AP1HDAC4HDAC6
SCHEMBL6291994 0.86 ATP6V1B1 (0.60) ATP6V1B1ATP6AP1HDAC4HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119677539-A Combination therapy for modulating lipid production 俄亥俄州创新基金会 2025-03-21 CN claimed
EP-4489865-A2 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION Ohio State Innovation Foundation (US) 2025-01-15 EP claimed
WO-2023172669-A9 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION OHIO STATE INNOVATION FOUNDATION (US) 2024-08-02 WO claimed
WO-2023172669-A2 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION OHIO STATE INNOVATION FOUNDATION (US) 2023-09-14 WO claimed
US-20250177367-A1 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION OHIO STATE INNOVATION FOUNDATION 2025-06-05 US disclosed
CN-119677539-A Combination therapy for modulating lipid production 俄亥俄州创新基金会 2025-03-21 CN disclosed
EP-4489865-A2 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION Ohio State Innovation Foundation (US) 2025-01-15 EP disclosed
US-20240352406-A1 BIOCOMPATIBLE CONDITIONED CELL MEDIUM COMPOSITIONS AND USES THEREOF CELLUM BIOMEDICAL, INC. 2024-10-24 US disclosed
WO-2023172669-A9 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION OHIO STATE INNOVATION FOUNDATION (US) 2024-08-02 WO disclosed
CN-118045230-A Artificial periosteum 奥索赛尔有限公司 2024-05-17 CN disclosed
WO-2023172669-A2 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION OHIO STATE INNOVATION FOUNDATION (US) 2023-09-14 WO disclosed
US-20230262698-A1 DEVICE AND METHOD FOR ALLOCATING RESOURCES IN WIRELESS COMMUNICATION SYSTEM SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-08-17 US disclosed
US-11673885-B2 γ-diketones as Wnt/β-catenin signaling pathway activators BIOSPLICE THERAPEUTICS, INC. (US) 2023-06-13 US disclosed
US-20230053726-A1 GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS VICKERS-SPLICE CO-INVESTMENT LLC (KY) 2023-02-23 US disclosed
US-20220325236-A1 BIOCOMPATIBLE CONDITIONED CELL MEDIUM COMPOSITIONS AND USES THEREOF CELLUM BIOMEDICAL, INC. 2022-10-13 US disclosed
US-20220243177-A1 METHODS OF CULTURING QUIESCENT HEMATOPOIETIC STEM CELLS AND TREATMENT METHODS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-08-04 US disclosed
US-11358931-B2 Selective androgen receptor modulators (SARMs) and uses thereof LIGAND PHARMACEUTICALS INCORPORATED (US) 2022-06-14 US disclosed
US-11345884-B2 Biocompatible conditioned cell medium compositions and uses thereof CELLUM BIOMEDICAL, INC. (US) 2022-05-31 US disclosed
WO-2022086230-A1 DEVICE AND METHOD FOR ALLOCATING RESOURCES IN WIRELESS COMMUNICATION SYSTEM 삼성전자 주식회사 2022-04-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11358931-B2 Selective androgen receptor modulators (SARMs) and uses thereof AR, NR5A1, SHBG ATP6V1B1 4088/4885ATP6AP1 4754/4885HDAC4 642/4885
US-20250177367-A1 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION ACACB, SREBF2, FASN ATP6V1B1 4302/4885ATP6AP1 4654/4885HDAC4 311/4885
US-20230053726-A1 GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS GSK3A, GSK3B, WNT1 ATP6V1B1 2000/4885ATP6AP1 3883/4885HDAC4 705/4885
US-11673885-B2 γ-diketones as Wnt/β-catenin signaling pathway activators GSK3A, GSK3B, WNT1 ATP6V1B1 2024/4885ATP6AP1 3959/4885HDAC4 579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.