SCHEMBL29547181

SCHEMBL29547181

Cc1ccc(C(NCCCC[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MDM2 Q00987 6/20 0.57
▸ MDM4 O15151 2/20 0.49
▸ TP53 P04637 2/20 0.49
▸ TLR2 O60603 2/20 0.46
▸ KMT2A Q03164 1/20 0.45
▸ TGM2 P21980 1/20 0.44
▸ CASP3 P42574 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6158363 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL436024 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL2288397 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL29792115 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL31681399 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL29362301 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL21192401 0.97 MDM2 (0.58) MDM2MDM4TP53TLR2KMT2A
SCHEMBL5967470 0.97 MDM2 (0.58) MDM2MDM4TP53TLR2KMT2A
SCHEMBL29401280 0.97 MDM2 (0.58) MDM2MDM4TP53TLR2KMT2A
SCHEMBL31614333 0.94 MDM2 (0.53) MDM2MDM4TP53TLR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357757-A1 SELF-PURIFIED NUCLEIC ACID ENCODED LIBRARIES PETROV, DIMITAR (CH) 2023-11-09 — — US disclosed
EP-4237008-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF Elucida Oncology, Inc. (US) 2023-09-06 — — EP disclosed
EP-4232578-A1 SELF-PURIFIED NUCLEIC ACID ENCODED LIBRARIES ETH Zurich (CH) 2023-08-30 — — EP disclosed
EP-4106820-A1 METHODS OF FUNCTIONALIZING NANOPARTICLES Elucida Oncology, Inc. (US) 2022-12-28 — — EP disclosed
EP-4103236-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF Elucida Oncology, Inc. (US) 2022-12-21 — — EP disclosed
WO-2022093793-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY, INC. (US) 2022-05-05 — — WO disclosed
WO-2022093794-A1 METHODS OF FUNCTIONALIZING NANOPARTICLES ELUCIDA ONCOLOGY, INC. (US) 2022-05-05 — — WO disclosed
WO-2022093800-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. (US) 2022-05-05 — — WO disclosed
WO-2022084486-A1 SELF-PURIFIED NUCLEIC ACID ENCODED LIBRARIES ETH ZURICH (CH) 2022-04-28 — — WO disclosed
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