SCHEMBL29401280

SCHEMBL29401280

Cc1ccc(C(NCCC[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MDM2 Q00987 6/20 0.58
▸ MDM4 O15151 2/20 0.50
▸ TP53 P04637 2/20 0.50
▸ TLR2 O60603 2/20 0.47
▸ CASP3 P42574 1/20 0.44
▸ KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21192401 1.00 MDM2 (0.58) MDM2MDM4TP53TLR2CASP3
SCHEMBL5967470 1.00 MDM2 (0.58) MDM2MDM4TP53TLR2CASP3
SCHEMBL29362301 0.97 MDM2 (0.57) MDM2MDM4TP53TLR2CASP3
SCHEMBL29547181 0.97 MDM2 (0.57) MDM2MDM4TP53TLR2CASP3
SCHEMBL2288397 0.97 MDM2 (0.57) MDM2MDM4TP53TLR2CASP3
SCHEMBL436024 0.97 MDM2 (0.57) MDM2MDM4TP53TLR2CASP3
SCHEMBL6158363 0.97 MDM2 (0.57) MDM2MDM4TP53TLR2CASP3
SCHEMBL29792115 0.97 MDM2 (0.57) MDM2MDM4TP53TLR2CASP3
SCHEMBL31681399 0.97 MDM2 (0.57) MDM2MDM4TP53TLR2CASP3
SCHEMBL23722974 0.94 MDM2 (0.56) MDM2MDM4TP53TLR2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070947-A1 CYCLIC CELL-PENETRATING PEPTIDE COMPOUNDS OHIO STATE INNOVATION FOUNDATION (US) 2026-03-12 — — US disclosed
US-20260001916-A1 CYCLIC CELL-PENETRATING PEPTIDE COMPOUNDS OHIO STATE INNOVATION FOUNDATION (US) 2026-01-01 — — US disclosed
US-20250304623-A1 PEPTIDES FOR INTRACELLULAR DELIVERY UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2025-10-02 — — US disclosed
EP-4543900-A1 PEPTIDES FOR INTRACELLULAR DELIVERY Universidade de Santiago de Compostela (ES) 2025-04-30 — — EP disclosed
CN-119768416-A Peptides for intracellular delivery 圣地亚哥-德孔波斯特拉大学 2025-04-04 — — CN disclosed
US-20240368227-A1 CYCLIC CELL-PENETRATING PEPTIDES WITH ONE OR MORE HYDROPHOBIC RESIDUES OHIO STATE INNOVATION FOUNDATION 2024-11-07 — — US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
US-11987647-B2 Cyclic cell-penetrating peptides with one or more hydrophobic residues OHIO STATE INNOVATION FOUNDATION (US) 2024-05-21 — — US disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
WO-2023247781-A1 PEPTIDES FOR INTRACELLULAR DELIVERY UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2023-12-28 — — WO disclosed
EP-4296274-A1 PEPTIDES FOR INTRACELLULAR DELIVERY Universidade de Santiago de Compostela (ES) 2023-12-27 — — EP disclosed
US-20230382947-A1 METHODS FOR PROXIMITY MEDIATED COUPLING OF A FIRST AGENT TO A SECOND AGENT UNIVERSITEIT GENT (BE) 2023-11-30 — — US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 — — CN disclosed
EP-4229069-A1 METHODS FOR PROXIMITY MEDIATED COUPLING OF A FIRST AGENT TO A SECOND AGENT Universiteit Gent (BE) 2023-08-23 — — EP disclosed
US-11674136-B2 DNA-templated macrocycle library PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-06-13 — — US disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
CN-115181157-A Method for preparing disulfide bond-containing polypeptide by solid-liquid phase combination 湖北健翔生物制药有限公司 2022-10-14 — — CN disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
WO-2022079127-A1 METHODS FOR PROXIMITY MEDIATED COUPLING OF A FIRST AGENT TO A SECOND AGENT UNIVERSITEIT GENT (BE) 2022-04-21 — — WO disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304623-A1 PEPTIDES FOR INTRACELLULAR DELIVERY LNPEP, TAP2, TMEM205 MDM2 2881/4885MDM4 1328/4885TP53 292/4885
US-20240368227-A1 CYCLIC CELL-PENETRATING PEPTIDES WITH ONE OR MORE HYDROPHOBIC RESIDUES VIP, LNPEP, TAP1 MDM2 3264/4885MDM4 1881/4885TP53 67/4885
US-11674136-B2 DNA-templated macrocycle library IDE, IAPP, POLRMT MDM2 938/4885MDM4 1827/4885TP53 130/4885
US-20260070947-A1 CYCLIC CELL-PENETRATING PEPTIDE COMPOUNDS SLC7A1, SLC38A7, SLC6A19 MDM2 4387/4885MDM4 3343/4885TP53 1476/4885
US-20260001916-A1 CYCLIC CELL-PENETRATING PEPTIDE COMPOUNDS SLC7A1, SLC38A7, SLC6A19 MDM2 4122/4885MDM4 2568/4885TP53 1243/4885
US-20230382947-A1 METHODS FOR PROXIMITY MEDIATED COUPLING OF A FIRST AGENT TO A SECOND AGENT DCLRE1A, CNBP, RNGTT MDM2 915/4885MDM4 1969/4885TP53 903/4885
US-11987647-B2 Cyclic cell-penetrating peptides with one or more hydrophobic residues VIP, LNPEP, TAP1 MDM2 3264/4885MDM4 1881/4885TP53 67/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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