Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.81 |
| ▸ | DRD2 | P14416 | 2/20 | 0.81 |
| ▸ | LMNA | P02545 | 1/20 | 0.81 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.81 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.81 |
| ▸ | HTR1A | P08908 | 1/20 | 0.81 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.81 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.81 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.81 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.81 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.81 |
| ▸ | DRD1 | P21728 | 1/20 | 0.81 |
| ▸ | DRD4 | P21917 | 1/20 | 0.81 |
| ▸ | HRH2 | P25021 | 1/20 | 0.81 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.81 |
| ▸ | HTR2A | P28223 | 1/20 | 0.81 |
| ▸ | HTR2C | P28335 | 1/20 | 0.81 |
| ▸ | HTR7 | P34969 | 1/20 | 0.81 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL141875 | 1.00 | ADRA2A (0.81) | ADRA2ADRD2LMNACHRM2CHRM4 | |
| SCHEMBL12260186 | 0.92 | DRD2 (0.81) | ADRA2ADRD2LMNACHRM2CHRM4 | |
| SCHEMBL17509819 | 0.91 | DRD2 (0.67) | ADRA2ADRD2LMNACHRM2CHRM4 | |
| SCHEMBL20959758 | 0.90 | CHRM1 (0.66) | ADRA2ADRD2LMNACHRM2CHRM4 | |
| Quetiapine SCHEMBL29360153 | 0.90 | DRD2 (1.00) | ADRA2ADRD2LMNACHRM2CHRM4 | |
| Quetiapine SCHEMBL4283801 | 0.90 | DRD2 (1.00) | ADRA2ADRD2LMNACHRM2CHRM4 | |
| Quetiapine SCHEMBL4638768 | 0.90 | DRD2 (1.00) | ADRA2ADRD2LMNACHRM2CHRM4 | |
| Quetiapine SCHEMBL7932 | 0.90 | DRD2 (1.00) | ADRA2ADRD2LMNACHRM2CHRM4 | |
| SCHEMBL2615342 | 0.89 | DRD2 (0.80) | ADRA2ADRD2LMNACHRM2CHRM4 | |
| Quetiapine SCHEMBL392703 | 0.89 | DRD2 (0.98) | ADRA2ADRD2LMNACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240345106-A1 | Chronic Disease Management Test to Inform Clinical Care of Patients with Chronic Conditions | AEGIS SCIENCES CORPORATION (US) | 2024-10-17 | — | — | US | disclosed |
| EP-4419255-A1 | READY-TO-CONSTITUTE ANALYTICAL PLATFORMS FOR CHEMICAL ANALYSES AND QUANTIFICATION OF ANALYTES IN BIOLOGICAL SAMPLES | Pinpoint Testing, LLC (US) | 2024-08-28 | — | — | EP | disclosed |
| EP-4221512-A1 | COMPOSITIONS, KITS AND METHODS FOR COLLECTING ANALYTE IN A SALIVA SAMPLE | Decima Diagnostics, LLC (US) | 2023-08-09 | — | — | EP | disclosed |
| WO-2023069732-A1 | READY-TO-CONSTITUTE ANALYTICAL PLATFORMS FOR CHEMICAL ANALYSES AND QUANTIFICATION OF ANALYTES IN BIOLOGICAL SAMPLES | PINPOINT TESTING, LLC (US) | 2023-04-27 | — | — | WO | disclosed |
| WO-2022072467-A1 | COMPOSITIONS, KITS AND METHODS FOR COLLECTING ANALYTE IN A SALIVA SAMPLE | DECIMADX, LLC (US) | 2022-04-07 | — | — | WO | disclosed |