Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 10/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 6/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193250 | 0.79 | SSTR3 (0.57) | CTSLKDM1AMAOA | |
| SCHEMBL27388030 | 0.79 | TGM2 (0.69) | TGM2CTSLHDAC1HDAC2 | |
| SCHEMBL27388031 | 0.79 | TGM2 (0.69) | TGM2CTSLHDAC1HDAC2 | |
| SCHEMBL2268022 | 0.79 | SIRT5 (0.57) | TGM2 | |
| Hydrochloric Acid SCHEMBL10943848 | 0.78 | SIRT5 (0.56) | TGM2 | |
| Hydrochloric Acid SCHEMBL10884941 | 0.78 | SIRT5 (0.56) | TGM2 | |
| SCHEMBL5052635 | 0.78 | PPIA (0.42) | TGM2MAOA | |
| SCHEMBL10481501 | 0.77 | CTSL (0.43) | TGM2CTSLCTSB | |
| SCHEMBL17289476 | 0.77 | SIRT5 (0.55) | TGM2 | |
| Bromide SCHEMBL9447770 | 0.77 | MEN1 (0.38) | TGM2CTSLMMP1MMP2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100022018-A1 | RAPID DETECTION OF SULFHYDRYL COMPOUNDS USING A PAPAIN BASED ASSAY | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-01-28 | — | — | US | disclosed |
| WO-2008066832-A2 | RAPID DETECTION OF SULFHYDRYL COMPOUNDS USING A PAPAIN BASED ASSAY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-06-05 | — | — | WO | disclosed |