SCHEMBL29551131

SCHEMBL29551131

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nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 1/20 0.41
▸ ACE P12821 1/20 0.41
▸ CPA1 P15085 1/20 0.41
▸ ACE2 Q9BYF1 1/20 0.41
▸ CTSD P07339 9/20 0.39
▸ ENPEP Q07075 5/20 0.36
▸ PSENEN Q9NZ42 1/20 0.36
▸ TERT O14746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31257047 0.93 MME (0.43) MMEACECPA1ACE2CTSD
SCHEMBL29448562 0.89 MME (0.46) MMEACECPA1ACE2CTSD
SCHEMBL34464920 0.89 OPRD1 (0.38) MMEACECPA1ACE2CTSD
SCHEMBL29387536 0.87 MME (0.43) MMEACECPA1ACE2CTSD
SCHEMBL29926236 0.86 MME (0.50) MMEACECPA1ACE2CTSD
SCHEMBL29551119 0.85 DPP4 (0.38) MMECTSD
SCHEMBL30051101 0.84 ALDH1A1 (0.47) MMEACECPA1ACE2ENPEP
SCHEMBL30051636 0.84 MME (0.53) MMEACECPA1ACE2ENPEP
SCHEMBL29445234 0.83 BACE1 (0.40) MMEACECPA1ACE2CTSD
SCHEMBL31129093 0.82 NPSR1 (0.38) MMECTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11339152-B2 Inhibitors VIVORYON THERAPEUTICS N.V. 2022-05-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11339152-B2 Inhibitors GLUL, QPCT, GLS MME 2046/4885ACE 747/4885CPA1 1566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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