Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL28059508 | 0.88 | PREP (0.33) | PREPCHRM2CHRM1CHRM3KDM4E | |
| SCHEMBL1838102 | 0.83 | PREP (0.37) | PREPCHRM2CHRM1CHRM3MAPT | |
| SCHEMBL28856336 | 0.82 | CHRM2 (0.38) | PREPCHRM2CHRM1CHRM3MAPT | |
| Hydrochloric Acid SCHEMBL28241841 | 0.82 | PREP (0.36) | PREPCHRM2CHRM1CHRM3MAPT | |
| SCHEMBL30014423 | 0.80 | GPR119 (0.31) | PREPCHRM2CHRM1CHRM3NR1H2 | |
| SCHEMBL28113304 | 0.80 | SIGMAR1 (0.32) | NR1H2 | |
| SCHEMBL28222533 | 0.79 | MAPK1 (0.35) | PREPKDM4EMAPTTHRBNR1H2 | |
| SCHEMBL28223429 | 0.79 | SIGMAR1 (0.32) | NR1H2 | |
| SCHEMBL28099175 | 0.78 | CHRM2 (0.31) | PREPCHRM2CHRM1CHRM3 | |
| Pyrrole SCHEMBL28865869 | 0.77 | GPR119 (0.32) | PREPNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022032484-A1 | PYRIDAZINE-3-FORMAMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 北京诺诚健华医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |